Bilateral Neck Pyomyositis Caused byStaphylococcus capitisandStaphylococcus saccharolyticusin a Diabetic Adult

Abstract

We report a case of pyomyositis of the paraspinal neck muscles caused by two coagulase-negative staphylococci: Staphylococcus capitis and Staphylococcus saccharolyticus. Inflammation in the spermatic cords was an additional feature of this infection. Treatment with six weeks of first-generation cephalosporin therapy resulted in complete clinical and radiological resolution.

An unusual Staphylococcus saccharolyticus spondylodiscitis post kyphoplasty: a case report

“…S. saccharolyticus is a lesser known coagulase-negative staphylococcus [ 1 ]. Although it is usually considered a skin contaminant, it can cause endocarditis, bone infection, or pyomyositis, which may be associated with poor outcome (Table 1 ) [ 2 – 5 , 9 – 13 ]. In addition to the tissue-invasive factors that have been unraveled, the dependence on anaerobic conditions is considered to favor the ability to invade human tissue, while biofilm production may contribute to the colonization of medical devices [ 6 ].…”

“…Staphylococcus saccharolyticus (formerly known as Peptococcus saccharolyticus ) is a rarely encountered coagulase-negative staphylococcus and the only anaerobic species of the genus Staphylococcus [ 1 ]. Although it is usually considered a non-pathogenic microorganism of the human skin flora with no particular known tropism to generate specific infections, occasional reports suggest a pathogenic potential through miscellaneous rare deep-seated infections [ 2 – 5 ]. Little is known on its virulence factors, pathogenesis, and determinants of infection.…”

An unusual Staphylococcus saccharolyticus spondylodiscitis post vertebroplasty, a case report

“…saccharolyticus is a little known coagulase-negative staphylococcus [1]. While it is usually considered as a skin contaminant, it is able to cause e.g., endocarditis, bone infection or pyomyositis, some of them with poor outcome (Table 1) [2][3][4][5][9][10][11][12][13].In addition to the tissue-invasive factors that have been unraveled, the dependence on anaerobic conditions is considered to inherently favor the ability to invade human tissue while biofilm production may contribute to colonize medical devices [6]. Further research is needed to better understand S. Saccharolyticus virulence and the risk of infection.…”

“…The rare reported infections (9 to our knowledge) have often been fatal (3 out of the 7 available outcomes, (Table 1).Timely treatment may be critical. Comorbidities favoring opportunistic organisms to cause infection are unevenly reported: prosthetic heart valves (10,13), poor oral hygiene (2), type II diabetes (5), to which we can add important tobacco use, alcoholism and cachexia in this patient Last but not least, infection control procedures designed to prevent infection following vertebroplasty procedure may require some advance to improve infection prevention in patients with poorer condition.…”

“…Staphylococcus saccharolyticus(formerly Peptococcus saccharolyticus) is a rarely encountered coagulase-negative staphylococcus and the only anaerobic species of the genus Staphylococcus [1]. While it is usually considered as a non-pathogenic microorganism of the human skin flora with no particular known tropism to generate specific infections, occasional reports suggest a pathogenic potential through miscellaneous rare deep-seated infections [2][3][4][5]. Little is known on its virulence factors, pathogenesis and determinants of infection.…”