Bilateral native knee septic arthritis due to <i>Propionibacterium acnes</i>; a case report and review of literature

Arain, Abdul; Cole, Keegan; Moral, Muhammad Z.; Thadani, Sean; Rosenbaum, Andrew J.

doi:10.1002/ccr3.2298

Cited by 2 publications

(7 citation statements)

References 13 publications

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“…Considering that C. acnes is a commensal microorganism with low pathogenicity, identification as an etiologic agent may be challenging since its growth in microbiological cultures can be interpreted as contamination. It is recommended that cultures be incubated for at least 14 days [ 1 , 4 , 6 , 7 ] to avoid misinterpretation of results, together with an adequate collection technique and handling of microbiological samples to prevent contamination [ 1 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

“…The following case illustrates a rare native knee septic arthritis caused by Cutibacterium acnes (C. acnes). This gram-positive bacillus is identified as a common agent of prosthetic shoulder infection, as well as other orthopaedic devices [1][2][3][4]. The clinical course is indolent and lacks typical signs of infection [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

“…This gram-positive bacillus is identified as a common agent of prosthetic shoulder infection, as well as other orthopaedic devices [1][2][3][4]. The clinical course is indolent and lacks typical signs of infection [4][5][6]. The most frequent site of colonization of C. acnes is the shoulder, accounting for higher infection rates in the upper body [7].…”

Section: Introductionmentioning

confidence: 99%

“…However, infection of native joints by this pathogen is still widely underdiagnosed in clinical practice. To our knowledge, there are a total of seven reported cases of native knee C. acnes septic arthritis [ 2 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

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Native Knee Septic Arthritis Due to Cutibacterium acnes: A Case Report

Santos¹,

Peres²,

Barros³

et al. 2022

Cureus

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Commensal skin anaerobes have been described as causative agents of prosthetic joint infections. Infection of native joints by these agents are, however, less common. We present the case of a 34-year-old male with recurrent joint effusion following closed trauma to the knee, four years ago, refractory to corticosteroid injections and several arthrocenteses. A synovial biopsy revealed Cutibacterium acnes infection leading to antibiotic therapy with clindamycin, and the patient was referred to orthopaedic and submitted to arthroscopic lavage. Atypical cartilage lesions, resembling the "growth of bacterial colonies", were found in the tibial plateaus with repeated isolation of C. acnes. Inpatient treatment with penicillin and vancomycin was conducted, followed by an oral course of amoxicillin, with no further registered recurrences. In this case, the authors describe a rare cause of native knee septic arthritis while highlighting the importance of repeated microbiology studies and adequate collection technique and sample handling, in order to better ascertain whether the isolated agent represents a contaminated sample or a true infection.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Native Knee Septic Arthritis Due to Cutibacterium acnes: A Case Report

Santos¹,

Peres²,

Barros³

et al. 2022

Cureus

View full text Add to dashboard Cite

show abstract

“…However, C acnes is increasingly being recognized as causative pathogen of serious infections 1‐4 . The bacterium is described as the responsible pathogen in prosthetic joint infections, 6 infections associated with implantable devices, 5 septic arthritis, 8 and post‐operative infections for instance after ocular 9 and brain 1‐4,10,11 surgery.…”

Section: Discussionmentioning

confidence: 99%

Intracerebral abscess due to Cutibacterium acnes after lung transplantation

Bos

Vleeschouwer

Raemdonck

et al. 2020

Transplant Infectious Dis

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Cutibacterium (C) acnes, a Gram‐positive bacterium that is part of the commensal flora, is increasingly noticed as an opportunistic pathogen in serious infections in both immunocompromised and immunocompetent patients. The indolent character and often difficult identification because of its slow growth contribute to delayed diagnosis or underdiagnosis. This report highlights a unique case of a lung transplant recipient with a C acnes intracerebral abscess, and we recommend including this organism in such differential diagnosis. A 66‐year‐old woman, 2 years after bilateral lung transplantation for chronic obstructive pulmonary disease, presented with frontal headache, without other complaints, and with normal neurological examination. Magnetic resonance imaging showed an extensive lesion in the right frontal lobe with extensive perilesional edema. Given the broad differential diagnosis, stereotactic brain biopsy was performed and culture became positive for C acnes. She was treated with intravenous ceftriaxone for 8 weeks and per oral clindamycin for 6 months, as well as corticosteroids in tapered dose. There was a rapid favorable clinical and radiographic evolution.

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Bilateral native knee septic arthritis due to Propionibacterium acnes; a case report and review of literature

Abstract: Propionibacterium acnes should be considered in any case of indolent septic arthritis. Cultures should be followed for 2 weeks as our cultures were negative for 7 days before growing P. acnes . Irrigation and debridement followed by antibiotics is the standard of care.

Cited by 2 publications

References 13 publications

Native Knee Septic Arthritis Due to Cutibacterium acnes: A Case Report

Native Knee Septic Arthritis Due to Cutibacterium acnes: A Case Report

Intracerebral abscess due to Cutibacterium acnes after lung transplantation

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