Bilateral multifocal congenital simple hamartoma of the retinal pigment epithelium

Mohan, Roshni; Yadav, Divya; Behera, SourabhPrasad

doi:10.4103/ijo.ijo_1858_21

Cited by 1 publication

(1 citation statement)

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“…In contrast to previous reports where CSHRPE presented as a solitary mass, our case revealed two separate heavily pigmented masses and smaller, less pigmented intraretinal masses in close proximity to each other [ 20 ]. The presence of less pigmented areas with hyperreflectivity and posterior shadowing in our case may suggest secondary structural changes surrounding the tumor or the presence of another cluster of tumor cells.…”

Section: Discussioncontrasting

confidence: 99%

Multifocal Congenital Simple Hamartoma of the Retinal Pigment Epithelium: A Multimodal Imaging Case Study

Khadamy,

Elmi Sadr

2024

Cureus

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Congenital simple hamartoma of the retinal pigment epithelium (CSHRPE) is a rare benign tumor often detected incidentally during routine eye exams. We present a case of multifocal CSHRPE in a 32-year-old Hispanic woman, emphasizing the diagnostic challenges posed by its presentation and the pivotal role of multimodal imaging in accurate diagnosis. Despite initial difficulties due to a history of trauma and pigmented fundus, advanced imaging techniques, including optical coherence tomography (OCT), OCT angiography (OCTA), fluorescein angiography (FA), and indocyanine green angiography (ICGA), facilitated a precise diagnosis. Notably, OCTA revealed high signal intensity and flow at the largest nodule site while FA and ICGA exhibited characteristic blockage patterns. Moreover, smaller nodules exhibited OCT findings supporting the theory of islands of retinal pigment epithelium (RPE) cells proliferating ectopically within the retina. Our case underscores the importance of comprehensive imaging assessment in distinguishing CSHRPE from other lesions, contributing to a deeper understanding of this rare ocular condition.

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Section: Discussioncontrasting

confidence: 99%