Bilateral macular choroiditis following Chikungunya virus infection

Chanana, Bhuvan; Azad, Raj Vardhan; Nair, Sridevi

doi:10.1038/sj.eye.6702863

Cited by 34 publications

(28 citation statements)

References 4 publications

(5 reference statements)

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“…However more recent reports reveal both mild as well as vision threatening ocular complications [102][103][104][105][106]. Ocular symptoms usually occur after a latent period of a month to year; however few concurrent presentations have also been reported [102,105].…”

Section: Ocular Diseasementioning

confidence: 93%

“…Posterior pole or macular retinochoroiditis appear relatively more specific and carries very poor visual prognosis (Fig. 11) [103,104,106]. Chikungunya retinitis is similar to herpetic retinitis however markedly less vitreous reaction and confluent posterior pole retinitis can differentiate Chikungunya from the acute retinal necrosis which is characterized by intense vitritis and peripheral multifocal or disseminated retinitis [103,104].…”

Section: Posterior Uveitismentioning

confidence: 95%

“…Patients may present with history of loss of vision, color vision defect, central or centrocecal scotoma and peripheral field defects [102][103][104][105][106]. Patients with posterior uveitis may have normal anterior segment and intraocular pressure is normal.…”

Section: Posterior Uveitismentioning

confidence: 96%

“…It is either unilateral or bilateral, affecting both the genders in all age groups. Two distinct presentations are seen in this infectious uveitis including anterior and posterior uveitis [102][103][104][105][106].…”

Section: Ocular Diseasementioning

confidence: 98%

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Novel infectious agents causing uveitis

et al. 2009

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In any patient with uveitis, an infectious cause should be ruled out first. The differential diagnosis includes multiple well-known diseases including herpes, syphilis, toxoplasmosis, tuberculosis, bartonellosis, Lyme disease, and others. However, clinician should be aware of emerging infectious agents as potential causes of systemic illness and also intraocular inflammation. Air travel, immigration, and globalization of business have overturned traditional pattern of geographic distribution of infectious diseases, and therefore one should work locally but think globally. This review recapitulates the systemic and ocular manifestations of several emergent infectious diseases relevant to the ophthalmologist including Rickettsioses, West Nile virus infection, Rift valley fever, Dengue fever, and Chikungunya. Retinitis, chorioretinitis, retinal vasculitis, and optic nerve involvement have been associated with these emergent infectious diseases. The diagnosis of any of these infections is usually based on pattern of uveitis, systemic symptoms and signs, and specific epidemiological data and confirmed by detection of specific antibody in serum. A systematic ocular examination, showing fairly typical fundus findings, may help establish an early clinical diagnosis, which allows prompt, appropriate management.

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Section: Ocular Diseasementioning

confidence: 93%

Section: Posterior Uveitismentioning

confidence: 95%

Section: Posterior Uveitismentioning

confidence: 96%

Section: Ocular Diseasementioning

confidence: 98%

See 2 more Smart Citations

Novel infectious agents causing uveitis

et al. 2009

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“…4). Associated occlusive vasculitis, accurately detected by FA, is also common [1,2,3,25,26,27]. Other posterior segment involvements include optic neuritis, neuroretinitis, central retinal artery occlusion, and exudative retinal detachment [25,26,27,28,29].…”

Section: Chikungunya Virus Infectionmentioning

confidence: 99%

New Infectious Etiologies for Posterior Uveitis

Khairallah

Kahloun²,

Yahia³

et al. 2012

Ophthalmic Res

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Emergent and resurgent arthropod vector-borne diseases are major causes of systemic morbidity and death and expanding worldwide. Among them, viral and bacterial agents including West Nile virus, Dengue fever, Chikungunya, Rift Valley fever, and rickettsioses have been recently associated with an array of ocular manifestations. These include anterior uveitis, retinitis, chorioretinitis, retinal vasculitis and optic nerve involvement. Proper clinical diagnosis of any of these infectious diseases is based on epidemiological data, history, systemic symptoms and signs, and the pattern of ocular involvement. The diagnosis is usually confirmed by the detection of a specific antibody in serum. Ocular involvement associated with emergent infections usually has a self-limited course, but it can result in persistent visual impairment. There is currently no proven specific treatment for arboviral diseases, and therapy is mostly supportive. Vaccination for humans against these viruses is still in the research phase. Doxycycline is the treatment of choice for rickettsial diseases. Prevention, including public measures to reduce the number of mosquitoes and personal protection, remains the mainstay for arthropod vector disease control. Influenza A (H1N1) virus was responsible for a pandemic human influenza in 2009, and was recently associated with various posterior segment changes.

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Chikungunya

Mahendradas¹

2017

Emerging Infectious Uveitis

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Bilateral macular choroiditis following Chikungunya virus infection

Cited by 34 publications

References 4 publications

Novel infectious agents causing uveitis

Novel infectious agents causing uveitis

New Infectious Etiologies for Posterior Uveitis

Chikungunya

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