2001
DOI: 10.1046/j.1365-263x.2001.00215.x
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Bilateral macrodontia of mandibular second premolars: a case report

Abstract: Macrodontia of single teeth is rare. This has been reported on only six occasions in scientific journals when affecting mandibular second premolars with associated morphological anomalies. The large crown size causes problems with eruption, and disrupts the dentition. There are consequent inherent difficulties for the extraction of these teeth. Once erupted, their anatomy predisposes them to caries. Most cases are seen in children, before interventive surgery has been completed. The morphological anomalies of … Show more

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Cited by 26 publications
(27 citation statements)
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References 12 publications
(48 reference statements)
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“…This is in agreement with the finding of 0.2% from Sweden (13). Macrodontia of a single tooth is rare (20). Enamel hypoplasia was the most prevalent dental anomaly in this study at 2.8%, which is higher than the figure of 1.5% reported in Japanese children (2), but lower than 3.5% found among Brazilians (21).…”
Section: Discussionsupporting
confidence: 92%
“…This is in agreement with the finding of 0.2% from Sweden (13). Macrodontia of a single tooth is rare (20). Enamel hypoplasia was the most prevalent dental anomaly in this study at 2.8%, which is higher than the figure of 1.5% reported in Japanese children (2), but lower than 3.5% found among Brazilians (21).…”
Section: Discussionsupporting
confidence: 92%
“…These signaling molecules affect both epithelial and mesenchymal cells and also their reciprocal interactions. [11][12][13][14] The mode of evolutionary modification in molarization of premolar is because of the overlapping expression of these signaling molecules and transcription domains in enamel knot (as seen in seals and ungulates). [15] The literature suggests that all six Dlx genes exhibit complex expression patterns in the developing teeth during the formation of transient structures within the enamel organ known as the enamel knot, enamel cord, and enamel navel in the cap stage, suggesting its role in tooth morphogenesis.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, Thomas and Sharpe stated that the patterning of dentition is also under the control of Dlx-1 and Dlx-2 genes which are specifically involved in patterning of molar tooth development, so any aberrancy in expression of this group of genes is also responsible for cuspal and morphological defects. [11][12][13][14][15] DD, a rare anomaly of unknown etiology, is classified into two types, radicular DD as Type I and coronal DD as Type II. In Type I, both the deciduous and permanent dentitions are affected.…”
Section: Discussionmentioning
confidence: 99%
“…Macrodontia is usually associated with systemic disturbances or syndromes such as insulin-resistant diabetes,2 otodental syndrome,3,4 facial hemihyperplasia,5,6 KBG syndrome,7 Ekman-Westborg-Julin syndrome,8 and 47, XYY syndrome 9. Isolated form of macrodontia has been rarely reported 10–13. The prevalence of macrodont permanent teeth is 0.03–1.9%,1416 with a higher frequency in males 15,16.…”
Section: Introductionmentioning
confidence: 99%