Bilateral Laser Interstitial Thermal Therapy for Butterfly Gliomas Compared With Needle Biopsy: A Preliminary Survival Study

Daggubati, Lekhaj C.; Ramos-Fresnedo, Andres; Merenzon, Martin A.; Bhatia, Shovan; Morell, Alexis A.; Berry, Katherine M.; Chandar, Jay; Shah, Ashish H.; Komotar, Ricardo J.; Ivan, Michael E.

doi:10.1227/ons.0000000000000850

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…Median overall survival was 4.3 months in the biopsy alone group and 10.3 months in the biopsy + LITT group ( P = 0.035). Bilateral LITT for bGBM can be performed safely and shows early improvements in progression-free survival and long-term survival outcomes in these patients ( 38 ). A recent meta-analysis reported the use of LITT in newly diagnosed and relapsed high-grade gliomas.…”

Section: Laser-induced Thermal Therapy Of Tumormentioning

confidence: 99%

Current status and research progress of minimally invasive treatment of glioma

Wu,

Zhou,

Gao

et al. 2024

Front. Oncol.

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Glioma has a high malignant degree and poor prognosis, which seriously affects the prognosis of patients. Traditional treatment methods mainly include craniotomy tumor resection, postoperative radiotherapy and chemotherapy. Although above methods have achieved remarkable curative effect, they still have certain limitations and adverse reactions. With the introduction of the concept of minimally invasive surgery and its clinical application as well as the development and progress of imaging technology, minimally invasive treatment of glioma has become a research hotspot in the field of neuromedicine, including photothermal treatment, photodynamic therapy, laser-induced thermal theraphy and TT-Fields of tumor. These therapeutic methods possess the advantages of precision, minimally invasive, quick recovery and significant curative effect, and have been widely used in clinical practice. The purpose of this review is to introduce the progress of minimally invasive treatment of glioma in recent years and the achievements and prospects for the future.

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Section: Laser-induced Thermal Therapy Of Tumormentioning

confidence: 99%

Current status and research progress of minimally invasive treatment of glioma

Wu,

Zhou,

Gao

et al. 2024

Front. Oncol.

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Safety and Efficacy of Laser Interstitial Thermal Therapy as Upfront Therapy in Primary Glioblastoma and IDH-Mutant Astrocytoma: A Meta-Analysis

Pandey,

Chandla,

Mekonnen

et al. 2024

Cancers

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Although primary studies have reported the safety and efficacy of LITT as a primary treatment in glioma, they are limited by sample sizes and institutional variation in stereotactic parameters such as temperature and laser power. The current literature has yet to provide pooled statistics on outcomes solely for primary brain tumors according to the 2021 WHO Classification of Tumors of the Central Nervous System (WHO CNS5). In the present study, we identify recent articles on primary CNS neoplasms treated with LITT without prior intervention, focusing on relationships with molecular profile, PFS, and OS. This meta-analysis includes the extraction of data from primary sources across four databases using the Covidence systematic review manager. The pooled data suggest LITT may be a safe primary management option with tumor ablation rates of 94.8% and 84.6% in IDH-wildtype glioblastoma multiforme (GBM) and IDH-mutant astrocytoma, respectively. For IDH-wildtype GBM, the pooled PFS and OS were 5.0 and 9.0 months, respectively. Similar to rates reported in the prior literature, the neurologic and non-neurologic complication rates for IDH-wildtype GBM were 10.3% and 4.8%, respectively. The neurologic and non-neurologic complication rates were somewhat higher in the IDH-mutant astrocytoma cohort at 33% and 8.3%, likely due to a smaller cohort size.

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Bilateral Laser Interstitial Thermal Therapy for Butterfly Gliomas Compared With Needle Biopsy: A Preliminary Survival Study

Cited by 2 publications

References 25 publications

Current status and research progress of minimally invasive treatment of glioma

Current status and research progress of minimally invasive treatment of glioma

Safety and Efficacy of Laser Interstitial Thermal Therapy as Upfront Therapy in Primary Glioblastoma and IDH-Mutant Astrocytoma: A Meta-Analysis

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