Bilateral glomus tumor treated with PET-CT based conformal radiotherapy: a case report

Onal, Cem; Yuksel, Oznur; Topkan, Erkan; Pehlivan, Berrin

doi:10.4076/1757-1626-2-8402

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…Females are five to six times more affected than males [4,33,34]. The most common presenting symptoms include pulsatile tinnitus, hearing loss, and otalgia, whereas the most common clinical finding is retrotympanc mass, which is evident during initial otoscopic examination [3,4].…”

Section: Clinical Featuresmentioning

confidence: 99%

Long-Term Surgical Outcome of Class A and B Tympanomastoid Paragangliomas

Yilala,

Fancello,

Fancello

et al. 2024

Cancers

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Objective: To analyze the long-term facial function as well as overall postoperative condition in surgically treated tympanomastoid PGL patients. Study Design: Retrospective study. Method: The medical records of patients with surgically managed class A and B tympanomastoid PGLs between 1983 and 2023 were thoroughly evaluated. Result: Our center has treated a total of 213 cases of tympanomastoid PGL surgically. The mean age of patients was 54, and the male-to-female ratio was 1:6. The most common symptoms at presentation were hearing loss (80%), pulsatile tinnitus (77%), and vertigo (15%). According to the modified Fisch classification, 45% of the cases were classified as class A (A1 and A2), while 55% were classified as class B (B1, B2, and B3). All class A and most class B1 and B2 tumors were removed either with transcanal or retroauricular-transcanal approaches. However, more advanced class B3 lesions were removed with subtotal petrosectomy (SP) along with middle ear obliteration. Facial nerve outcome was excellent in all class A and B cases, while chances of postoperative paresis slightly increased with the size and extent of the tumor (p < 0.05). The hearing outcome is excellent for class A1, A2, B1, and B2 tumors, whereas more advanced class B3 cases have a loss of air conduction (AC) and increased bone conduction (BC) threshold (p < 0.05). Complete surgical removal was achieved in 97% of our cases. The most common late complication was permanent TM perforation (7%), and the recurrence rate was 3%. Conclusions: Tympanomastoid PGL represents the most common neoplasm of the middle ear space. The most frequent presenting symptoms include pulsatile tinnitus and hearing loss, whereas the presence of retrotympanic mass was evident in all cases at the time of initial otoscopic evaluation. Proper documentation of facial function and audiometric evaluation are crucial elements of preoperative workup. The most preferred preoperative radiologic examination is high-resolution computer tomography (HRCT), whereas magnetic resonance imaging (MRI) with or without gadolinium enhancement is reserved for cases with a dilemma of carotid artery or jugular bulb involvement. The main goal of tympanomastoid PGL treatment is complete disease removal with preservation of hearing and facial functions. Surgical treatment remains the preferred treatment modality with the benefits of complete disease removal, lower rate of recurrence and complication, and acceptable postoperative hearing level. Here, we present our 40 years of experience, which, to the very best of our knowledge, is the largest series of tympanomastoid PGL in the English literature.

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Section: Clinical Featuresmentioning

confidence: 99%

Long-Term Surgical Outcome of Class A and B Tympanomastoid Paragangliomas

Yilala,

Fancello,

Fancello

et al. 2024

Cancers

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“…TBPs affect women five to six times more often than men [11,13] but the reason for this distinct predilection still evades us. A female preponderance of 95% seen in our series of TMPs is perhaps the maximum reported in the literature [4,5,12,14,15].…”

Section: Clinical Features and Imaging Protocolsmentioning

confidence: 99%

Long term surgical and hearing outcomes in the management of tympanomastoid paragangliomas

Patnaik¹,

Prasad²,

Medina³

et al. 2015

American Journal of Otolaryngology

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Current Approaches and Recent Developments in the Management of Head and Neck Paragangliomas

et al. 2014

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Head and neck paragangliomas (HNPGLs) are rare neuroendocrine tumors belonging to the family of pheochromocytoma/paraganglioma neoplasms. Despite advances in understanding the pathogenesis of these tumors, the growth potential and clinical outcome of individual cases remains largely unpredictable. Over several decades, surgical resection has long been the treatment of choice for HNPGLs. However, increasing experience in various forms of radiosurgery has been reported to result in curative-like outcomes, even for tumors localized in the most inaccessible anatomical areas. The emergence of such new therapies challenges the traditional paradigm for the management of HNPGLs. This review will assist and guide physicians who encounter patients with such tumors, either from a diagnostic or therapeutic standpoint. This review will also particularly emphasize current and emerging knowledge in genetics, imaging, and therapeutic options as well as the health-related quality of life for patients with HNPGLs.

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Bilateral glomus tumor treated with PET-CT based conformal radiotherapy: a case report

Cited by 3 publications

References 19 publications

Long-Term Surgical Outcome of Class A and B Tympanomastoid Paragangliomas

Long-Term Surgical Outcome of Class A and B Tympanomastoid Paragangliomas

Long term surgical and hearing outcomes in the management of tympanomastoid paragangliomas

Current Approaches and Recent Developments in the Management of Head and Neck Paragangliomas

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