“…In most patients, DBS alleviates parkinsonian motor signs, shortens 'off' periods, and reduces druginduced dyskinesias, dystonia, and motor fluctuations (Rodriguez-Oroz et al, 2004;Anderson et al, 2005;Weaver et al, 2005;Portman et al, 2006;Bronstein et al, 2011). In general, both GPi-and STN-DBS are more effective than medical management alone to alleviate motor deficits in patients with advanced PD (Just and Ostergaard, 2002;Martinez-Martin et al, 2002;Troster et al, 2003;Lezcano et al, 2004;Diamond and Jankovic, 2005;Erola et al, 2005;Halbig et al, 2005;Lyons and Pahwa, 2005;Deuschl et al, 2006;Rodrigues et al, 2007a, b;Montel and Bungener, 2009;Weaver et al, 2009b;Zahodne et al, 2009). In contrast to patients with GPi-DBS, those with STN-DBS are often able to substantially reduce the medication doses (Breit et al, 2004; …”