Bilateral clear cell acanthoma of the areola and nipple: good response to topical corticosteroids

Abstract

Clear cell acanthoma is a rare, epidermal tumor not common in the area of the nipples; indeed, the literature describes only 8 cases, all showing unilateral presentation. We here report the first case of bilateral clear cell acanthoma with good response to topical corticosteroids.Case reportA sixteen-year old girl presented with 2 excrescent, fleshy, and exudative tumor masses in both nipples and areola mammae. A biopsy was conducted and confirmed clear cell acanthoma histopathologically. Treatment with strong corticosteroids resulted in rapid improvement and resolution. After one year of follow-up, the patient developed atopic dermatitis.DiscussionWe describe the first case of bilateral clear cell acanthoma localized in the nipple/areola that resolved with powerful corticosteroids, suggesting a reactive etiology of the lesion.

Clear Cell Acanthoma on the Areola

“…CCA of the nipple or areola is a very rare finding, to our knowledge previously reported in only 10 patients [2,5]. All but one of the cases were in women and predominantly occurred within the second to third decade of life.…”

Bilateral Pale Cell Acanthoma of Mammary Glands in 13 Years Old Boy: Clinical Case

“…Были предложены различные способы лечения акантомы Дегоса. Хирургическое иссечение и криодеструкция в настоящее время признаны наиболее эффективными методами [11]. Однако в результате такого лечения часто остаются шрамы, что приводит к нарушению психологического состояния больного [12].…”