2015
DOI: 10.1001/jamaophthalmol.2015.1128
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Bilateral Choroidopathy and Serous Retinal Detachments During Ipilimumab Treatment for Cutaneous Melanoma

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Cited by 51 publications
(24 citation statements)
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References 7 publications
(7 reference statements)
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“…Rarely described, retinal involvement such as bilateral multifocal choroidal neovascularization may potentially result in retinal or preretinal hemorrhages, retinal edema, and retinal detachment similar to age‐related macular degeneration . In addition, retinal involvement has also been described in two patients suspected of having Vogt‐Koyanagi‐Harada syndrome .…”
Section: Episcleritis/uveitis and Disorders Of The Orbitmentioning
confidence: 99%
See 1 more Smart Citation
“…Rarely described, retinal involvement such as bilateral multifocal choroidal neovascularization may potentially result in retinal or preretinal hemorrhages, retinal edema, and retinal detachment similar to age‐related macular degeneration . In addition, retinal involvement has also been described in two patients suspected of having Vogt‐Koyanagi‐Harada syndrome .…”
Section: Episcleritis/uveitis and Disorders Of The Orbitmentioning
confidence: 99%
“…Selten wird von einer Beteiligung der Retina berichtet wie eine bilaterale multifokale choroidale Neovaskularisation mit der möglichen Folge von retinalen oder präretinalen Hämorrhagien, Ödemen der Retina und einer Netzhautablösung mit Ähnlichkeiten zur altersbedingten Makuladegeneration [ 39,40 ] . Ferner trat eine retinale Beteiligung bei zwei Patienten im Rahmen eines vermuteten Vogt-Koyanagi-Harada-Syndroms auf [ 41,42 ] .…”
Section: Episkleritis/uveitis Und Erkrankungen Der Orbitaunclassified
“…Recently, Mantopoulos et al [26] and Crews et al [27] published two cases in which bilateral choroidopathy and serous retinal detachments occurred due to choroidal vascular injury, during ipilimumab treatment for cutaneous melanoma. The cases have similarities to the case of ipilimumab-induced VKH syndrome; however, patients had significantly less intraocular inflammation, no symptoms of VKH syndrome and no hyperfluorescence on fluorescein angiography.…”
Section: Ocular and Orbital-side-effects Of Checkpoint Inhibitorsmentioning
confidence: 99%
“…They can be almost the same as typical VKH, but untypical clinical features are more common . For example, incomplete symptoms and signs might occur in VKH‐like syndrome, such as patients having no symptoms of meningism, hearing loss or vitiligo . Furthermore, differences in the sequence of symptoms and signs may occur.…”
Section: Vogt‐koyanagi‐harada Like Syndromementioning
confidence: 99%
“…17 For example, incomplete symptoms and signs might occur in VKH-like syndrome, such as patients having no symptoms of meningism, hearing loss or vitiligo. 19 Furthermore, differences in the sequence of symptoms and signs may occur. Patients might have no prodromal stage and the vitiligo might occur before the ocular signs.…”
Section: Symptoms and Signsmentioning
confidence: 99%