Bilateral Choroid Plexus Metastasis from Papillary Thyroid Carcinoma: Case Report and Review of the Literature

Sharifi, Guive; Bakhtevari, Mehrdad Hosseinzadeh; Alghasi, Mohsen; Nosari, Masood Asghsri; Rahmanzade, Ramin; Rezaei, Omidvar

doi:10.1016/j.wneu.2015.05.027

Cited by 14 publications

(18 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Observations Metastatic disease to the CP is uncommon, with only 42 reports in the literature from any solid tumor primary malignancy. [1][2][3][4] Thyroid carcinomas are rare as well, representing 1% of all malignancies. 6 Thyroid carcinoma metastasizes to the brain in only 0.9%-1.5% of cases and has been reported in the CP in eight prior cases.…”

Section: Discussionmentioning

confidence: 99%

“…The choroid plexus (CP) is an uncommon location for metastases from central nervous system (CNS) and non-CNS malignancies, with only 42 cases reported in the literature. [1][2][3][4] Eight cases of CP metastases from thyroid carcinoma have been reported previously, with only two confirmed cases of multifocal CP metastases known to date. 1,[5][6][7][8][9][10][11] All eight cases involved differentiated thyroid carcinoma (DTC), namely papillary or follicular subtypes.…”

mentioning

confidence: 99%

“…[1][2][3][4] Eight cases of CP metastases from thyroid carcinoma have been reported previously, with only two confirmed cases of multifocal CP metastases known to date. 1,[5][6][7][8][9][10][11] All eight cases involved differentiated thyroid carcinoma (DTC), namely papillary or follicular subtypes. Only two known cases of multifocal metastasis to the CP from any malignancy exist in the literature, originating from papillary thyroid carcinoma and renal cell carcinoma, respectively.…”

mentioning

confidence: 99%

“…Only two known cases of multifocal metastasis to the CP from any malignancy exist in the literature, originating from papillary thyroid carcinoma and renal cell carcinoma, respectively. 1,12 Brain metastasis from differentiated thyroid carcinoma suggests a poor prognosis. Differentiated thyroid carcinoma without brain metastasis has a 90% 10-year survival rate, whereas the presence of any brain metastases from DTC is associated with a 67% mortality rate and a median survival rate of 12.4 months from diagnosis.…”

mentioning

confidence: 99%

See 3 more Smart Citations

Multifocal metastases to choroid plexus from papillary thyroid carcinoma: illustrative case

Beach

Olszewski²,

Thomas³

et al. 2021

Journal of Neurosurgery: Case Lessons

View full text Add to dashboard Cite

BACKGROUND Choroid plexus metastases are extremely rare from all types of malignancy, with only 42 cases reported in the literature thus far. Most of these originate from renal cell carcinoma and present as a solitary choroid plexus lesion; only two cases of multifocal choroid plexus metastases have been reported to date. OBSERVATIONS The authors report the third case of multifocal metastases to the choroid plexus, that of a 75-year-old man who developed three measurable choroid plexus lesions approximately 3.5 years after undergoing total thyroidectomy and chemotherapy for papillary thyroid carcinoma. He underwent intraventricular biopsy of the largest lesion and subsequently died of hydrocephalus after opting for comfort care only. LESSONS This is the third case of multifocal choroid plexus metastasis in the literature and the second case of multifocal metastasis from thyroid carcinoma. As such, the natural disease course is not well characterized. This case is compared with the previous eight reports of choroid plexus metastases from thyroid carcinoma, seven of which involved solitary lesions. The eight prior cases are evaluated with attention to treatment modalities used and factors potentially influencing prognosis, specifically those that might contribute to hydrocephalus, a reported complication for this pathology.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Multifocal metastases to choroid plexus from papillary thyroid carcinoma: illustrative case

Beach

Olszewski²,

Thomas³

et al. 2021

Journal of Neurosurgery: Case Lessons

View full text Add to dashboard Cite

show abstract

“…2 By the time of ocular involvement, most patients have evidence of widely disseminated metastatic disease as with this patient. 8 Current National Comprehensive Cancer Network guidelines recommend total thyroidectomy as the initial step if metastatic disease is apparent at the time of diagnosis of follicular thyroid carcinoma followed by post-operative use of radioactive iodine ablation. 5 The rationale for this approach is for optimal uptake of radioactive material in residual tissue without competition from the thyroid gland.…”

Section: Outcome and Follow-upmentioning

confidence: 99%

Bilateral Choroidal Metastases as Initial Presentation of Widespread Follicular Thyroid Cancer

Hong¹

2019

TMF

View full text Add to dashboard Cite

Malignant invasion of the central nervous system: the hidden face of a poorly understood outcome of prostate cancer

et al. 2018

View full text Add to dashboard Cite

Malignancies of the central nervous system include primary brain tumors and brain metastases, the latter being the major cause of intracranial neoplasms in adults. Although prostate cancer (PCa) brain metastases are not the most common source, recent data show that the relevance of prostate cancer brain metastases (PCBM) cannot be neglected. In this review, we focus on the molecular repertory as well as on the phenotypical similarities between PCBM and primary PCa, such as the cellular evolution and the maintenance of androgen-receptor expression. Moreover, the simultaneous occurrence of PCBM with other PCa metastatic sites and the significance of the clinical heterogeneity of the disease are also discussed. In addition, a potential relationship between the heterogeneous behavior exhibited by PCBM and the co-occurrence of malignant cell clusters with distinct genetic profiles is also hypothesized, as well as the prominent role of astrocytes in the establishment of PCBM.

show abstract

Bilateral Choroid Plexus Metastasis from Papillary Thyroid Carcinoma: Case Report and Review of the Literature

Cited by 14 publications

References 12 publications

Multifocal metastases to choroid plexus from papillary thyroid carcinoma: illustrative case

Multifocal metastases to choroid plexus from papillary thyroid carcinoma: illustrative case

Bilateral Choroidal Metastases as Initial Presentation of Widespread Follicular Thyroid Cancer

Malignant invasion of the central nervous system: the hidden face of a poorly understood outcome of prostate cancer

Contact Info

Product

Resources

About