Bilateral avascular necrosis of femoral heads after pelvic irradiation: A case report and systematic review

Abstract

The development of radiation induced changes in bone is related to multiple factors such as total dose, per fraction dose, irradiated volume, bone structure and localization, patient age, and chemo-radiotherapy. It is known that chang-es in bone occur after 30-40 Gy. There are very few publications on this subject in the literature, mostly case reports. Therefore, there is no definite consensus about the pathogenesis, diagnosis, and treatment. In this report, a case of avascular necrosis of bilateral femoral heads after pelvic radiotherapy will be presented and the relevant literature will be reviewed.