Bilateral areolar sebaceous hyperplasia in a Female

Guillermo, N.; Peñate, Yeray; Soler, Elena; Hernández‐Machín, Buenaventura; Montenegro, T.; Borrego, Leopoldo

doi:10.1111/j.1365-4632.2008.03856.x

Cited by 10 publications

(9 citation statements)

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“…[1][2][3][4][5][6][7][8][9][10][11] We have also not found any case of association of areolar sebaceous hyperplasia and ipsilateral breast carcinoma. Glazebrook et al 33 described 2 cases in which breast carcinoma mimicked an areolar dermal lesion on sonography, but this appearance was due to dermal infiltration by the carcinoma, whereas the histopathologic study demonstrated no adnexal or epidermal alterations.…”

Section: Discussionmentioning

confidence: 94%

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Areolar Sebaceous Hyperplasia With Underlying Primary Duct Carcinoma of the Breast in a Woman With Donohue Syndrome (Leprechaunism)

Fernández-Flores¹,

Valerdiz²,

Crespo³

et al. 2012

The American Journal of Dermatopathology

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Areolar hyperplasia is only reported when exaggerated, and even so, exaggerated areolar sebaceous hyperplasia is rare. We have recently seen a case of areolar sebaceous hyperplasia in a 32-year-old woman with Donohue syndrome (leprechaunism), who also had an invasive ductal carcinoma in the same breast. The patient showed typical "elfin-like" face with wide nostrils and thick lips, large and low-set ears, and dysplastic nails. The areola showed a yellowish thickened plaque of 5-cm diameter that corresponded to a hyperplasia of the sebaceous glands. Immunohistochemistry for the mismatch repair proteins (MLH1, MSH2, MSH6, and PMS2) was performed on the sebaceous hyperplasia and on the breast carcinoma, and no lack of expression of the markers was evidenced. We have found no other reported case of areolar sebaceous hyperplasia either in cases of breast carcinoma or in cases of leprechaunism.

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Section: Discussionmentioning

confidence: 94%

“…We have found 12 cases published in the literature, both in women and men. [1][2][3][4][5][6][7][8][9][10][11] Most of these cases were not associated with any relevant pathology.…”

Section: Introductionmentioning

confidence: 99%

Areolar Sebaceous Hyperplasia With Underlying Primary Duct Carcinoma of the Breast in a Woman With Donohue Syndrome (Leprechaunism)

Fernández-Flores¹,

Valerdiz²,

Crespo³

et al. 2012

The American Journal of Dermatopathology

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“…Although its cause is unknown, areolar sebaceous hyperplasia is notable because in two of the reported cases, it occurred after pregnancy 8 17. A third case was thought to be secondary to a thermal injury to the areola during childhood 18…”

Section: Discussionmentioning

confidence: 99%

Rare presentation of sebaceous hyperplasia

2014

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“…The disease was found to be bilateral in five women and two men, while in the remaining cases was unilateral. 2,3 Only two patients also had oral Fordyce spots, while to date there are no reports of ASH associated with genital Fordyce spots. Clinically, ASH may appear as a diffuse yellowish thickening or swelling of areola, yellowish isolated papules or, as in our case, yellowish plaques due to the confluence of minute papules.…”

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confidence: 93%