Bilateral and multifocal Warthin�s tumor of parotid gland: two case reports and review of literature

Nicolai, G; Ventucci, E; Antonucci, P; Costantino, Vincenzo; Brunelli, Giorgio; Mariani, G; Saltarel, Andrea; Lorè, B; Calabrese, L

doi:10.11138/orl/2014.7.1.025

Cited by 5 publications

(17 citation statements)

References 24 publications

(25 reference statements)

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“…Most of the Warthin's tumor patients were males (15 male patients and only one female patient of 79 years old). The proportion of male patients in this study was consistent with that in the previous studies [4] . According to previous studies, Warthin's tumor is related to smoking and hormones [5,6] .…”

Section: Resultssupporting

confidence: 92%

A Modified Mini Incision for The Surgery of Parotid Benign Tumor: A Retrospective Analysis of 48 Cases

Jin

Wei

Wang

et al. 2020

Preprint

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Background: Parotid neoplasm is a result of inadequate surgical incision during the treatment of head and neck cancers, and most of them are benign tumors. Hence, to explore a new surgical incision for parotid benign tumor in order to minimize the scar size on the premise of guaranteeing the safety of operation.Methods: We conducted a retrospective study of 48 patients who had undergone parotid surgeries from Jan. 01 2008 to Dec. 30 2014 at the department of otolaryngology, Jinshan Hospital of Fudan University. Histopathological examination confirmed benign parotid tumor (Warthin's tumor, pleomorphic adenoma, cysts, and monomorphic adenomas.) in all cases. All patients underwent a mini incision (cutting the skin directly on the surface of the tumor, and the incision was slightly longer than the diameter of the tumor). Results: Among the 48 cases, no recurrence and facial nerve injury were reported during the follow-up period of more than 4 years. Two cases of saliva fistula and one case of temporary facial nerve dysfunction were reported; however, they recovered quickly after symptomatic treatment.Conclusion: Extracapsular dissection is a safe and effective surgical procedure for the treatment of parotid benign tumor, and the postoperative scar is very small.

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Section: Resultssupporting

confidence: 92%

A Modified Mini Incision for The Surgery of Parotid Benign Tumor: A Retrospective Analysis of 48 Cases

Jin

Wei

Wang

et al. 2020

Preprint

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“…WT is categorised according to Seifert et al in four histological types, depending on the proportions of the epithelial component and lymphoid stroma . The most common type is that in which the epithelium and lymphoid stroma ratio is approximately equal, stroma‐poor type where the epithelial component is above 70%, stroma‐rich type with the lymphoid stromal component above 70% and metaplastic type.…”

Section: Histopathological Analysis Of Wtmentioning

confidence: 99%

“…The most common type is that in which the epithelium and lymphoid stroma ratio is approximately equal, stroma‐poor type where the epithelial component is above 70%, stroma‐rich type with the lymphoid stromal component above 70% and metaplastic type. In this metaplastic type or variant, the classic oncocytic epithelium and the lymphomatous stroma are partially replaced by squamous metaplasia and haemorrhagic and necrotising areas are also present …”

Section: Histopathological Analysis Of Wtmentioning

confidence: 99%

“…Different primary tumours or multiple tumours of salivary glands are rare and when they occur, the most common association with WT is other benign salivary gland tumours, primarily pleomorphic adenoma . Multiple tumours may be considered from three perspectives: according to their histological type with identical or different histology, time of development as synchronous or metachronous and localisation as unilateral, bilateral and multiple .…”

Section: Association With Other Salivary Gland Tumours and Other Extrmentioning

confidence: 99%

“…Thus, serial sections of the involved salivary gland reveal additional sub‐clinical lesions in 50% of cases. In addition to multicentric WT in one salivary gland, WT can also be found in multiple locations in different salivary glands and tissues …”

Section: Introductionmentioning

confidence: 99%

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Cytopathology and diagnostics of Warthin's tumour

Sučić

Ljubić²,

Perković³

et al. 2020

Cytopathology

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Warthin's tumour (WT) is a benign epithelial salivary tumour, one type of salivary adenoma. Histologically, WT is structured of two components, epithelial tissue that often lines cystic formations and lymphoid tissue in the tumour stroma. FNA is a reliable diagnostic approach in the diagnosis of salivary gland lesions allowing a highly accurate categorization of benign tumour‐like lesions, benign tumours and malignant tumours. In the proposed Milan reporting system of salivary gland lesions, WT is categorized in the IVA group of benign neoplasms. Accurate cytological diagnosis is straightforward when three characteristic components are present: oncocytes, either isolated or associated in clusters, lymphocytes and lymphoid cells and often an inflammatory/necrotic‐like substance. Also, specific features of scintigraphy and radiological imaging contribute to the diagnosis of WT. WT is categorized according to Seifert G. et al in 4 types, depending on the proportions of the epithelial component and lymphoid stroma. Differential cytopathological and pathohistological diagnosis include other salivary gland lesions with lymphoid, oncocytic epithelial and cystic components. In some cases, such as the metaplastic WT variant, there are additional cytopathological and histological diagnostic difficulties. Moreover, bilateral, multicentric or multiple and infrequently seen extra‐salivary localizations of WT are associated with further cytopathological diagnostic difficulties. Also, a rare possibility of malignant transformation of the epithelial or lymphoid component of WT as well as possible association with other primary tumours remains a challenge in accurate cytopathological and histological diagnosis of WT.

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