Bilateral adrenal primary tumor in Stage 4S neuroblastoma: The Italian experience and review of the literature

Revisiting the role of radiotherapy in the treatment of neuroblastoma 4S: 30 years of institutional experience and systematic review

“… All patients survived Muftakhova et al (2015) [34] 4 4 2 months 450–600 cGy in 3–4 fractions 3 of 4 patients (75 %) survived for 1 year or longer Not reported No response to treatment – 1 patient (after 1 month) Doré et al (2015) [23] 1 0 12 days 600 cGy in 4 fractions 1 of 1 patient (100 %) survived for 1 year Not observed All patients survived Langenberg-Ververgaert et al (2019) [33] 1 1 36 weeks 450 cGy in 2 fractions 1 of 1 patient (100 %) survived for 1 year At 20 months of age, the patient developed a recurrence in the right adrenal region. All patients survived Tas et al (2020) [12] 6 5 4 months Not specified 5 of 6 patients (83 %) survived for 13 years or longer Not reported Progressive disease – 1 patient (after 22 months) Montalto et al (2022) [47] 1 0 18 days Not specified 1 of 1 patient (100 %) survived for 21 years Not reported All patients survived …”