Bilateral acute angle-closure glaucoma after use of Fenox™ nasal drops

Khan, Miraj Ali; Watt, Laure; Hugkulstone, Charles E.

doi:10.1038/sj.eye.6700125

Cited by 18 publications

(9 citation statements)

References 8 publications

(8 reference statements)

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“…In fact, there was even one case where it was hypothesized that absorption of a nasal decongestant through the nasal mucosa used for a week triggered bilateral acute angle closure glaucoma in a patient. 11 , 12 Adrenergic agents such as salbutamol are commonly found in nebulizers and inhalers used in the management of asthma, flu remedies or rectal suppositories. Salbutamol is a beta-2-adrenergic receptor agonist that stimulates beta-2-adrenergic receptors in the ciliary body to promote aqueous humour secretion.…”

Section: Drugs Causing Acute Angle Closure Glaucomamentioning

confidence: 99%

A review of drug-induced acute angle closure glaucoma for non-ophthalmologists

Ah-kee

Egong

Shafi

et al. 2015

Qatar Medical Journal

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Acute angle closure glaucoma is an ophthalmic emergency and can lead to blindness if left untreated. Several types of drugs have the potential to precipitate acute angle closure glaucoma. These include adrenergic, cholinergic and anticholinergic, antidepressants, anticoagulants and sulfa-based agents. This article provides a basic overview of the risk factors and pathophysiologic mechanisms involved in angle closure glaucoma and focuses on drug-induced angle closure glaucoma for the non-ophthalmologist. A PubMed search limited to the English language was conducted to find relevant literature for the purpose of this article. Most attacks occur in subjects unaware that they are at risk due to innately narrow iridocorneal angles. Clinicians should always review medications in patients presenting with symptoms of acute angle closure glaucoma. The aim of this article is to bring this ophthalmic condition to the attention of clinicians, particularly those outside the field of ophthalmology who commonly prescribe these medications or see these patients prior to referring to ophthalmologists.

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Section: Drugs Causing Acute Angle Closure Glaucomamentioning

confidence: 99%

A review of drug-induced acute angle closure glaucoma for non-ophthalmologists

Ah-kee

Egong

Shafi

et al. 2015

Qatar Medical Journal

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“…Upper respirator tract infections and cold remedies may have the same effect. 30,73 Posterior segment pathological processes 74 or therapeutic procedures 75 occasionally cause a rise in IOP associated with transient angle [76][77][78] This last observation has prompted Quigley to suggest a choroidal vascular mechanism in some cases of PAC. 79 However, despite the increasing sophistication of our theoretical models of angle closure, we still do not fully understand the reason for closure in many cases.…”

Section: Mechanism Of Angle Closurementioning

confidence: 99%

Angle-closure glaucoma in East Asian and European people. Different diseases?

Foster

Johnson

et al. 2005

Eye

176

102

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In contrast to the pattern of disease in Europeans, primary angle closure has a higher prevalence and tends to be asymptomatic in East Asians. The higher prevalence is attributed to differences in anterior chamber and angle anatomy. Several studies suggest that central anterior chamber depth is shallower in East Asians than in Europeans, although this is not universally accepted. It is debated whether pupil block is the predominant mechanism of angle closure in Asian people. Meaningful comparison between studies is currently hindered by differences in patient selection, examination technique, and case definition; however, the major scientific deficiency is the paucity of prospective followup data to give an insight into natural history of the disease. This review examines the data on prevalence, risk factors, and mechanism of angle closure. Special consideration is given to limitations of methodology in research to date, with the intention of developing more robust data in future studies.

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“…20,[81][82][83] Ipratropium bromide, an anticholineric agent used to relive bronchoconstriction causes mydriasis and might precipitate an ACAG attack in susceptible individuals. 3,[84][85][86] Three of five patients who developed ACAG after receiving ipratropium and salbutamol experienced bilateral ocular involvement.…”

Section: Respiratory System Agentsmentioning

confidence: 99%

Non-steroidal drug-induced glaucoma

Razeghinejad

Pro

Katz

2011

Eye

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Numerous systemically used drugs are involved in drug-induced glaucoma. Most reported cases of non-steroidal drug-induced glaucoma are closed-angle glaucoma (CAG). Indeed, many routinely used drugs that have sympathomimetic or parasympatholytic properties can cause pupillary block CAG in individuals with narrow iridocorneal angle. The resulting acute glaucoma occurs much more commonly unilaterally and only rarely bilaterally. CAG secondary to sulfa drugs is a bilateral non-pupillary block type and is due to forward movement of iris-lens diaphragm, which occurs in individuals with narrow or open iridocorneal angle. A few agents, including antineoplastics, may induce open-angle glaucoma. In conclusion, the majority of cases with glaucoma secondary to non-steroidal medications are of the pupillary block closed-angle type and preventable if the at-risk patients are recognized and treated prophylactically.

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Bilateral acute angle-closure glaucoma after use of Fenox™ nasal drops

Cited by 18 publications

References 8 publications

A review of drug-induced acute angle closure glaucoma for non-ophthalmologists

A review of drug-induced acute angle closure glaucoma for non-ophthalmologists

Angle-closure glaucoma in East Asian and European people. Different diseases?

Non-steroidal drug-induced glaucoma

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