Bilateral Achromobacter xylosoxidans keratitis after laser in situ keratomileusis

Linke, Stephan J.; Skevas, Christos; Richard, Gisbert; Katz, Toam

doi:10.1016/j.jcrs.2010.03.024

Cited by 17 publications

(10 citation statements)

References 6 publications

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“…A. xylosoxidans has been isolated in cases of ear and eye infections (26,28,30), urinary tract infections (28,38), intra-abdominal infections (39), liver abscesses (4), soft tissue infections (5, 29), osteomyelitis (42), arthroplasty infections (37), meningitis (8,26,29,30), ventriculitis (35), endocarditis (1, 2, 41), and pneumonia (3, 10-13, 20, 32, 34, 39, 44). A. xylosoxidans has been isolated from multiple sources, including blood (3,9,11,16,18,28,33), cerebrospinal fluid (CSF) (8,26,29,30), stool, urine (28,38), sputum (40), skin, ear discharge (29,45), wounds (29), abscesses (4, 39), bone (42), joints (37), endocardium (1, 2, 41), ascites fluid (39), and corneal scrapings and vitreous humor fluid (14,22,27,31).…”

Section: Case Reportmentioning

confidence: 99%

Achromobacter xylosoxidans Infection Presenting as a Pulmonary Nodule Mimicking Cancer

et al. 2011

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Section: Case Reportmentioning

confidence: 99%

Achromobacter xylosoxidans Infection Presenting as a Pulmonary Nodule Mimicking Cancer

et al. 2011

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“…Serratia marcesens has been reported as a cause of microbial keratitis after PRK [27] and LASIK [28]. Bilateral Achromobacter xylosoxidans post-LASIK keratitis was reported as a polymicrobial infection in association with Aspergillus and coagulase-negative staphylococcal infection [29]. This patient required bilateral corneal grafts to control the infection.…”

Section: Gram-negative Organismsmentioning

confidence: 88%

Microbial Keratitis after Corneal Laser Refractive Surgery

Sharma¹,

Sharma

Wilkins

2011

Future Microbiol.

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Corneal laser refractive surgery is increasingly being performed on patients with the aim of improving unaided vision. Most candidates for surgery have excellent spectacle- or contact lens-corrected vision. Although microbial keratitis following refractive surgery is a rare complication, and usually has a good visual outcome, it can be sight-threatening. The spectrum of pathogens differs to other causes of microbial keratitis, such as contact lens-associated keratitis, and a different management approach is required. Postoperatively, patients are prescribed topical steroids and broad-spectrum topical antibiotics, typically fluoroquinolones. These do not cover unusual organisms, such as fungi, Nocardia, Acanthamoeba and some atypical mycobacteria. In post-laser-assisted in situ keratomileusis microbial keratitis, the lamellar flap should be lifted to acquire samples for specific microbiological examination, including these atypical organisms. Confocal microscopy is a noninvasive test that provides morphological information, and is operator dependent, but may assist in the rapid diagnosis of fungal, Acanthamoeba or Norcardia keratitis. PCR is not in widespread use, but has high sensitivity and specificity, and may facilitate early diagnosis and specific treatment of the causative organism, which is critical in obtaining the best clinical outcome.

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“…In their study, the symptoms of all patients except one were resolved with topical antibiotic therapy. Linke et al [24] also reported a case of bilateral Achromobacter xylosoxidans keratitis after LASIK.…”

Section: Discussionmentioning

confidence: 99%

Achromobacter xylosoxidansKeratitis after Contact Lens Usage

Park

Song

Koh

2012

Korean J Ophthalmol

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To report on Achromobacter xylosoxidans keratitis in two healthy patients who had worn contact lenses foran extended period of time. A 36-year-old female and a 21-year-old female visited our hospital with ocular pain and blurred vision. Both patients had a history of wearing soft contact lenses for over fve years with occasional overnight wear. At the initial presentation, a slit lamp examination revealed corneal stromal infiltrations and epithelial defects with peripheral neovascularization in both patients. Microbiological examinations were performed from samples of corneal scrapings, contact lenses, contact lens cases, and solution. The culture resulting from the samples taken from the contact lenses, contact lens cases, and solution were all positive for Achromobacter xylosoxidans. Confrming that the direct cause of the keratitis was the contact lenses, the frst patient was prescribed ceftazidime and amikacin drops sensitive to Achromobacter xylosoxidans. The second patient was treated with 0.3% gatifoxacin and fortifed tobramycin drops. After treatment, the corneal epithelial defects were completely healed, and subepithelial corneal opacity was observed. Two cases of Achromobacter xylosoxidans keratitis were reported in healthy young females who wore soft contact lenses. Achromobacter xylosoxidans should be considered a rare but potentially harmful pathogen for lens-induced keratitis in healthy hosts.

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Bilateral Achromobacter xylosoxidans keratitis after laser in situ keratomileusis

Cited by 17 publications

References 6 publications

Achromobacter xylosoxidans Infection Presenting as a Pulmonary Nodule Mimicking Cancer

Achromobacter xylosoxidans Infection Presenting as a Pulmonary Nodule Mimicking Cancer

Microbial Keratitis after Corneal Laser Refractive Surgery

Achromobacter xylosoxidansKeratitis after Contact Lens Usage

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