Bigels and multi-component organogels: An overview from rheological perspective

Shakeel, Ahmad; Farooq, Ujala; Gabriele, Domenico; Marangoni, Alejandro G.; Lupi, Francesca R.

doi:10.1016/j.foodhyd.2020.106190

Cited by 97 publications

(53 citation statements)

References 91 publications

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“…The solvent forms an external phase and can be hydrophobic or hydrophilic. The solvent is immobilized within the space of a three-dimensional network structure of the gelling agent [ 50 , 65 , 66 , 67 , 68 ].…”

Section: Polymeric Gels and Their Propertiesmentioning

confidence: 99%

“…Recently, there have been studies on new types of gels, such as emulgels (including nanoemulgels), bigels, aerogels, and on their potential in the dermal administration of medicinal substances [ 50 , 67 , 72 , 73 , 74 , 75 , 76 ].…”

Section: Polymeric Gels and Their Propertiesmentioning

confidence: 99%

“…This insolubility acts as a trigger for molecular self-assembly and subsequent organization as a function of concentration and temperature of the gelator. Ideally, the gelling agent must be cheap, easily available, inert, and safe, and it cannot react with other formulation constituents [ 67 , 70 , 83 ].…”

Section: Polymeric Gels and Their Propertiesmentioning

confidence: 99%

“…This transformation is usually caused by a physical phenomenon, i.e., surface and capillary forces, without affecting the chemical properties of the liquid phase. Usually, the bulk structure of organogels comes from the self-assembly of gelator molecules into a crystal lattice, micelles fibrils, or aggregates, which eventually arrange themselves to form a 3D network [ 50 , 67 , 138 , 139 , 140 ].…”

Section: Polymeric Gels and Their Propertiesmentioning

confidence: 99%

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Polymeric Gels and Their Application in the Treatment of Psoriasis Vulgaris: A Review

Kulawik‐Pióro

Miastkowska

2021

IJMS

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Psoriasis is a chronic skin disease, and it is especially characterized by the occurrence of red, itchy, and scaly eruptions on the skin. The quality of life of patients with psoriasis is decreased because this disease remains incurable, despite the rapid progress of therapeutic methods and the introduction of many innovative antipsoriatic drugs. Moreover, many patients with psoriasis are dissatisfied with their current treatment methods and the form with which the drug is applied. The patients complain about skin irritation, clothing stains, unpleasant smell, or excessive viscosity of the preparation. The causes of these issues should be linked with little effectiveness of the therapy caused by low permeation of the drug into the skin, as well as patients’ disobeying doctors’ recommendations, e.g., concerning regular application of the preparation. Both of these factors are closely related to the physicochemical form of the preparation and its rheological and mechanical properties. To improve the quality of patients’ lives, it is important to gain knowledge about the specific form of the drug and its effect on the safety and efficacy of a therapy as well as the patients’ comfort during application. Therefore, we present a literature review and a detailed analysis of the composition, rheological properties, and mechanical properties of polymeric gels as an alternative to viscous and greasy ointments. We discuss the following polymeric gels: hydrogels, oleogels, emulgels, and bigels. In our opinion, they have many characteristics (i.e., safety, effectiveness, desired durability, acceptance by patients), which can contribute to the development of an effective and, at the same time comfortable, method of local treatment of psoriasis for patients.

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Section: Polymeric Gels and Their Propertiesmentioning

confidence: 99%

Section: Polymeric Gels and Their Propertiesmentioning

confidence: 99%

Section: Polymeric Gels and Their Propertiesmentioning

confidence: 99%

Section: Polymeric Gels and Their Propertiesmentioning

confidence: 99%

See 2 more Smart Citations

Polymeric Gels and Their Application in the Treatment of Psoriasis Vulgaris: A Review

Kulawik‐Pióro

Miastkowska

2021

IJMS

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“…Accurately weighed quantity of organogelator such as fatty acids, fatty alcohol, lecithin, waxes, cyclodextrins steroids, and its derivatives, in predefined oil phase at a constant homogenization condition and temperature higher than melting point of the organogelator. The gellation will be formed when the temperature is brought down to room temperature 25°C [18][19][20][21][22][23][24].…”

Section: Preparation Of Oleogelmentioning

confidence: 99%

Bi-Gels: A Novel Material for Transdermal Drug Delivery

2021

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Bi-gels semi solid formulation is combination of organogel and hydrogel with better application property such as pharmaceutical and cosmetics. The main objective of this review is specially focuses on application of bi-gels as drug delivery vehicles by transdermal route. It contains two different phases which are polar and nonpolar due to which, it possess some significant features such as ability to deliver the hydrophilic and hydrophobic drugs which also have improved permeability of drugs, better spreading ability, and water wash ability. Hence, bigels have both organogels and hydrogels they can enhanced hydration of stratum corneum and also had an ability to manipulate the drug release rate from the dosage from.

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Application of Small‐Angle X‐Ray Scattering and Small‐Angle Neutron Scattering to Fat Mimetics

Gilbert

2023

Fat Mimetics for Food Applications

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Bigels and multi-component organogels: An overview from rheological perspective

Cited by 97 publications

References 91 publications

Polymeric Gels and Their Application in the Treatment of Psoriasis Vulgaris: A Review

Polymeric Gels and Their Application in the Treatment of Psoriasis Vulgaris: A Review

Bi-Gels: A Novel Material for Transdermal Drug Delivery

Application of Small‐Angle X‐Ray Scattering and Small‐Angle Neutron Scattering to Fat Mimetics

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