2022
DOI: 10.2196/36481
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Big Data Health Care Platform With Multisource Heterogeneous Data Integration and Massive High-Dimensional Data Governance for Large Hospitals: Design, Development, and Application

Abstract: Background With the advent of data-intensive science, a full integration of big data science and health care will bring a cross-field revolution to the medical community in China. The concept big data represents not only a technology but also a resource and a method. Big data are regarded as an important strategic resource both at the national level and at the medical institutional level, thus great importance has been attached to the construction of a big data platform for health care. … Show more

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Cited by 23 publications
(15 citation statements)
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References 36 publications
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“…WECODe links de-identified data from eight sources of EMR, demographic records, medical and discharge summaries, prescription records, surgery records, laboratory records, vital sign records, glucose monitoring records, and diagnosis records. The Big Data Platform at West China Hospital of Sichuan University (WCH-BDP) facilitates data storage and analysis [ 19 ].…”
Section: Methodsmentioning
confidence: 99%
“…WECODe links de-identified data from eight sources of EMR, demographic records, medical and discharge summaries, prescription records, surgery records, laboratory records, vital sign records, glucose monitoring records, and diagnosis records. The Big Data Platform at West China Hospital of Sichuan University (WCH-BDP) facilitates data storage and analysis [ 19 ].…”
Section: Methodsmentioning
confidence: 99%
“…This research used resources from the Duyu High Performance Computing Center, Sichuan University, and the Big Data Platform, West China Hospital (WCH-BDP), Sichuan University. 46 ■ RESULTS AND DISCUSSIONS HTRF-Based Screening. To discover new potent GnRH1R small molecule agonists, we detected inositol monophosphate (IP-1) accumulation, a downstream marker for GnRH1R activation, in GnRH1R-expressing HEK-293T cells (HEK-293T−GnRH1R) after ligand stimulation using a homogeneous time-resolved fluorescence (HTRF) assay.…”
Section: ■ Materials and Methodsmentioning
confidence: 99%
“…MD trajectories were analyzed using MDAnalysis, MDTraj, , and in-house scripts. This research used resources from the Duyu High Performance Computing Center, Sichuan University, and the Big Data Platform, West China Hospital (WCH-BDP), Sichuan University …”
Section: Methodsmentioning
confidence: 99%
“…This research used resources from the Duyu High Performance Computing Center, Sichuan University, and Big Data Platform at West China Hospital of Sichuan University (WCH-BDP). 74 ■ ABBREVIATIONS USED NSAIDs, non-steroidal anti-inflammatory drugs; Δ9-THC, (−)-trans-Δ9-tetrahydrocannabinol; CBD, cannabidiol; SAR, structure−activity relationship; CHO, Chinese hamster ovary; HATU, 2-(7-azabenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate; DIPEA, N,N-diisopropylethanamine; DCM, dichloromethane; DMF, N,N-dimethylformamide; NanoBiT, NanoLuc Binary Technology; PK, pharmacokinetic; ERK, extracellular signal-regulated kinase…”
Section: Notesmentioning
confidence: 99%