Bifunctional Pincer Catalysts for Chemoselective Transfer Hydrogenation and Related Reactions

Abstract

A comparative study on the chemoselective transfer hydrogenation of nitroarenes to anilines and related processes using FA as the hydrogen source is described; these processes are catalyzed by a series of pincer catalysts equipped with different functional groups in the secondary coordination sphere. Some new (4 and 5) as well as previously reported (1-3) catalysts belonging to the family of bifunctional PC(sp 3 )P pincer complexes were employed in this study The reported com-Scheme 1. Secondary ligand-substrate-attracting interactions stabilize the H-bound transition state.[a]

Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles

“…2-Chloro-phenylamine ( 1e ) [43]: The product was obtained as a colorless liquid in a yield of 40% (0.09 g). 1 H NMR (600 MHz, CDCl 3 ) δ 7.31 – 7.19 (m, 1H), 7.04 (dd, J = 10.2, 4.2 Hz, 1H), 6.68 (dd, J = 16.0, 6.6 Hz, 2H), 4.00 (s, 2H).…”

Quantitative Sustainability Assessment of Flow Chemistry–From Simple Metrics to Holistic Assessment

“…A very useful tool to steer sustainable flow protocols is the implementation of heterogeneous catalysts − in combination with the use of biomass- or waste-derived chemicals, mainly used as solvents. − In this section, two examples have been selected in which, by the evaluation of green metrics, the improvements of environmental efficiency have been quantified.…”

Willstätter‐Vorlesung: D. Gelman / Otto‐Roelen‐Medaille: F. Glorius / European Chemistry Gold Medal: M. Parrinello

“…Gelman untersucht Katalysatoren mit Ligand‐Metall‐Kooperation, im Besonderen modulare dreidimensionale “Pincer”‐Komplexe mit zusätzlichen funktionellen Gruppen für Wasserstofftransferreaktionen. Er gehört dem Internationalen Beirat des European Journal of Inorganic Chemistry an, zu dessen Themenheft “Advanced Complex Inorganic Nanomaterials” seine Gruppe ein Full Paper über difunktionelle “Pincer”‐Katalysatoren beisteuerte …”