Bifidogenic effect of dietary fiber and resistant starch from leguminous on the intestinal microbiota of rats

Queiroz-Monici, Keila da Silva; Costa, Giovana E.A.; Silva, Neusely da; Reis, Soely Maria Pissini Machado; Oliveira, Admar Costa de

doi:10.1016/j.nut.2004.09.019

Cited by 73 publications

(37 citation statements)

References 23 publications

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“…Pulse-based foods have the potential to alter satiety and the gut microbiota due to their protein and carbohydrate (starch and fiber) content [19]. Human and rodent studies as well as epidemiological evidence suggest improvements in metabolic health with the consumption of various pulses [19][20][21][22][23][24][25][26][27]. Recent studies have shown that consumption of whole pulses for 8 weeks reduced symptoms of the metabolic syndrome in overweight and obese adults [27].…”

Section: Introductionmentioning

confidence: 99%

“…The whole yellow PFL was associated with a significant shift in microbial composition with predominant changes in the Firmicutes phylum [22]. Moreover, a randomized controlled trial demonstrated that healthy adults consuming raffinose, a chickpea oligosaccharide, had increased bifidobacteria [28]; similarly, rats fed pea and chickpea-containing diets had greater bifidobacteria abundance [20]. Based on previous work, it is clear that there are common but also some unique physiologic effects attributable to the various fractions of pulses, the most notably examined to date being yellow peas.…”

Section: Introductionmentioning

confidence: 99%

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Yellow pea fiber improves glycemia and reduces Clostridium leptum in diet-induced obese rats

2014

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Yellow pea fiber improves glycemia and reduces Clostridium leptum in diet-induced obese rats

2014

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“…A lower pH value in the intestine is associated with a decrease in colonic cancer risk in humans [8] . It is likely that SCFA suppress infectious intestinal diseases by inhibiting putrefactive and pathogenic bacteria such as Escherichia coli and Clostridium , and by promoting increases in lactic acid-producing bacteria such as Lactobacillus and Bifidobacterium [26] . In same way, the potato flake diets decreased the pH value.…”

Section: Discussionmentioning

confidence: 99%

Feeding Potato Flakes Affects Cecal Short-Chain Fatty Acids, Microflora and Fecal Bile Acids in Rats

et al. 2008

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Background/Aims: Feeding rats potato resistant starch improves large bowel health; however, there is little information on the physiological effects of preprocessed starch like potato flakes in animal experiments. The present study was designed to investigate the effects of the consumption of various colored potato (white, red and purple) flakes on cecal fermentation and fecal bile acid excretions in rats. Methods: The control group was fed a basal diet (BD) containing α-cornstarch for 4 weeks. The potato flake-treated groups were fed one of the following diets containing a mixture of 299.5 g/kg α-cornstarch plus 250 g/kg Hokkai kogane flakes (HK, white), Hokkai No. 91 flakes (H91, red) or Hokkai No. 92 flakes (H92, purple). Results: There were no significant differences in the body weight, food intake and cecum weight among the groups. Cecal pH values in the HK, H91 and H92 groups were significantly lower than that in the BD group, and matter excretion in the H91 group was significantly higher than in the BD and HK groups. Cecal short-chain fatty acid (SCFA) concentrations in the HK, H91 and H92 groups were significantly higher than in the BD group, and the molar ratio of butyrate to total SCFA in the HK, H91 and H92 groups was greatly increased compared with the BD group. Rats fed the HK, H91 and H92 potato flake diets presented significantly higher counts of total anaerobes in the cecum than rats fed the BD. The cecal Lactobacillus count in the H91 group was significantly increased compared to the BD group and the Bifidobacterium count was similar for all groups. Fecal total bile acid excretion in the H92 flake group and secondary bile acid excretions in the H91 and H92 groups were significantly greater than those in the other groups and in the BD and HK groups, respectively. Conclusion: The results indicate that potato flakes act like resistant starch and raise bowel SCFA, probably through anaerobic bacterial activities and fermentation of residual starch. These actions are helpful for the improvement of the colonic environment.

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“…[11] Studies indicate that seeds of P. vulgaris were found to have activities such as enhancement of the bifidogenic, antioxidant, antimutagenic, anticarcinogenic, and antihyperglycemic effects. [12][13][14][15][16] Our previous study demonstrated in vitro antiurolithiatic activity of ethanolic seed extract of P. vulgaris on CaOx crystallization. [17] No studies were carried out on the in vivo antiurolithiatic activity.…”

Section: Original Articlementioning

confidence: 99%

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Prasad¹

2017

IJGP

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Objective: The present study was aimed to evaluate the antiurolithiatic potential of the ethanolic extract of the seed of Phaseolus vulgaris (EPV). Materials and Methods: Calcium oxalate urolithiasis in male Wistar rats was induced by ethylene glycol (EG) (0.75% v/v) and ammonium chloride (1% w/v) administration in drinking water. Cystone (750 mg/kg, p.o.) was used as a standard drug, and EPV was administered at doses of 200 and 400 mg/kg, p.o. Both preventive and curative effects of EPV were evaluated. Urinary biochemical parameters such as calcium, oxalate, phosphate, uric acid and creatinine; deposition of calcium and oxalate in the kidney; and serum uric acid, creatinine, and blood urea nitrogen (BUN) were assessed. Creatinine clearance was calculated. Oxalate associated oxidative stress in the kidney was assessed by estimating in vivo antioxidant parameters such as lipid peroxidation, superoxide dismutase, catalase, and reduced glutathione. Histopathological studies of the kidney were carried out. Results: In the preventive and curative disease-control groups, urinary excretion of calcium, oxalate, and their deposition in the kidney were significantly increased. Elevated levels of phosphate and uric acid in urine and uric acid, creatinine, and BUN in serum were observed in both the control groups. Creatinine clearance was reduced in the control groups. On treatment with cystone and EPV, all the urinary, serum biochemical, and oxidative stress parameters were reversed to almost normal values. Cystone and EPV significantly restored the in vivo antioxidant enzymes by decreasing the lipid peroxidation in the kidney. This study demonstrated the antiurolithiatic activity of the ethanolic extract of P. vulgaris seeds against EG-induced renal calculi in Wistar rats.

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Bifidogenic effect of dietary fiber and resistant starch from leguminous on the intestinal microbiota of rats

Cited by 73 publications

References 23 publications

Yellow pea fiber improves glycemia and reduces Clostridium leptum in diet-induced obese rats

Yellow pea fiber improves glycemia and reduces Clostridium leptum in diet-induced obese rats

Feeding Potato Flakes Affects Cecal Short-Chain Fatty Acids, Microflora and Fecal Bile Acids in Rats

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