“…The complex role of depolarizing E GABA in network synchronization and excitability has recently been investigated in a num-ber of studies. The value of E GABA has been found to dramatically affect action potential generation and firing rate modulation (Gulledge and Stuart, 2003;Morita et al, 2006;Prescott et al, 2006;Saraga et al, 2008). Most importantly, E GABA interacts with such factors as the speed of the synapse, the synaptic delay, and the dynamics of spike generation to determine the stability and synchrony of neuronal oscillations (Jeong and Gutkin, 2005;Stiefel et al, 2005;Morita et al, 2006;Vida et al, 2006; see also Jedlicka and Backus, 2006).…”