Bibliometric and visualization analysis of macrophages associated with osteoarthritis from 1991 to 2021

Yang, Zhen; Lin, Jianjing; Li, Hui; He, Zihao; Wang, Kai; Lei, Liandi; Li, Hao; Xing, Dan; Lin, Jianhao

doi:10.3389/fimmu.2022.1013498

Cited by 16 publications

(19 citation statements)

References 62 publications

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“…The number of articles that had the key word of OA in their title generated by the EU, Non-EU and Geo-EU Countries increased from the year of 2007 to 2021. Our findings were in line with previous studies that analyzed the trend in publications previously (Zhang et al, 2022;Yang et al, 2022;Hu et al, 2022;Patel et al, 2022;Muthu et al, 2022;Molyneux et al, 2022;Ren et al, 2021;Li et al, 2021;Zhang et al, 2020;Liu et al, 2020;Li et al, 2020 R;Chen et al, 2021;Xing et al, 2018;Gupta & Gupta, 2018;Gao et al, 2020).Furthermore, we focused on comparing the impact of OA research from Europe by analyzing trends from the years of 2007 to 2021 for articles published in the EU, non-EU associated and geographically European countries. We limited our search to articles only and did not include all documents.…”

Section: Discussionsupporting

confidence: 90%

“…Our findings for these parameters were in line with previous studies (Wang K et al, 2019;Chen et al, 2021;Wang et al, 2020;Zhang et al, 2022;Li et al, 2020;Patel et al, 2022). We did not use CiteSpace or VOSviewer software's for bibliometric and visualization analysis (Yang et al, 2022). Instead, we wanted to focus on academic impact of multi-disciplinary and collaborative studies.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Multi-Disciplinary Approach and Collaborative Studies Increase the Impact of Osteoarthritis Publications: A European Perspective

Koçak,

Nürnberger,

Aulin

et al. 2023

Preprint

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Scientometric analysis of osteoarthritis (OA) publication was randomly undertaken during the last five years. A multi-disciplinary and collaborative scientometric study was designed and conducted. We analyzed publication and citation trends of OA articles between 2007 and 2021 in the Clarivate-Web of Science and InCites databases for the European Union (EU), the non-EU associated and the geographically European (Geo-EU) countries. We furthermore evaluated citations, Citation Impact (CI), Category Normalized Citation Impact (CNCI) and the Impact Relative to World (IREW) distributions. Leading countries, authors, institutions and funding agencies were defined. The impact of multi-disciplinary and collaborative studies was determined. Publication and citation numbers on OA research increased from 2007 to 2021. European citations, CI, CNCI and IREW distributions were higher than that of the World baseline. The United Kingdom, the Netherlands and Germany preceded OA research in Europe. UDICE-French Research Universities, University of Oxford and Assistance Publique Hopitaux Paris were leading European institutions. Funding was mostly from non-European resources. European countries with a higher gross national income quantitatively dominated the outcome and impact of OA research. We found that multi-disciplinary and collaborative studies were mostly published in higher journal quartiles. We conclude that collaboration and multi disciplinarity increases the impact in OA research. Methodology of quantifying impact could be applied to other research areas in the future.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Multi-Disciplinary Approach and Collaborative Studies Increase the Impact of Osteoarthritis Publications: A European Perspective

Koçak,

Nürnberger,

Aulin

et al. 2023

Preprint

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“…Leung et al reported that concentrations of TNF-α, IL-6, and IL-8 are associated with pain on movement, with only TNF-α being involved in the exacerbation of the pain at rest, which is characteristic of sensitized pain in the synovial fluid of knee OA (KOA) [33]. Further, it is known that these pro-inflammatory cytokines are primarily expressed by synovial monocytes and macrophages in OA joints [34][35][36]. Further, CD14-positive macrophages regulate NGF via pro-inflammatory cytokine production in the synovial membrane of KOA [34][35][36].…”

Section: Molecules Involved In Ps and Cs In Oamentioning

confidence: 99%

“…Further, it is known that these pro-inflammatory cytokines are primarily expressed by synovial monocytes and macrophages in OA joints [34][35][36]. Further, CD14-positive macrophages regulate NGF via pro-inflammatory cytokine production in the synovial membrane of KOA [34][35][36]. Synovial CD163 mRNA expression is positively correlated with pain at rest, while CD163+CD14 low macrophages expressing TNF-α might be a major contributor to hip OA (HOA) pain [34].…”

Section: Molecules Involved In Ps and Cs In Oamentioning

confidence: 99%

Mechanisms of Peripheral and Central Sensitization in Osteoarthritis Pain

Ohashi¹,

Uchida²,

Fukushima³

et al. 2023

Cureus

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Pain, the primary symptom of osteoarthritis (OA), reduces both the quality and quantity of life for patients. The pathophysiology of OA pain is complex and often difficult to explain solely by radiological structural changes. One reason for this discrepancy is pain sensitization (peripheral sensitization [PS] and central sensitization [CS]) in OA. Thus, an understanding of pain sensitization is important when considering treatment strategies and development for OA pain. In recent years, pro-inflammatory cytokines, nerve growth factors (NGFs), and serotonin have been identified as causative agents that induce peripheral and central sensitization and are becoming therapeutic targets for OA pain. However, the characteristics of the clinical manifestations of pain sensitization elicited by these molecules remain unclear, and it is not well understood who among OA patients should receive the therapeutic intervention. Thus, this review summarizes evidence on the pathophysiology of peripheral and central sensitization in OA pain and the clinical features and treatment options for this condition. While the majority of the literature supports the existence of pain sensitization in chronic OA pain, clinical identification and treatment of pain sensitization in OA are still in their infancy, and future studies with good methodological quality are needed.

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“…Hu et al revealed 10 hot microRNAs of chondrocytes in OA and their potential targets based on bibliometrics ( Hu et al, 2022 ). Yang et al (2022) performed a bibliometric analysis of the knowledge structure and trends in OA-related macrophage research. Zhang et al (2022) visualized the historical evolution and future trends of hyaluronic acid for OA.…”

Section: Introductionmentioning

confidence: 99%

Bibliometric insights from publications on subchondral bone research in osteoarthritis

Wen

Wang

et al. 2022

Front. Physiol.

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Background: The role of subchondral bone in the pathogenesis of osteoarthritis has received continuous attention worldwide. To date, no comprehensive bibliometric analysis of this topic has been carried out. The purpose of this study was to investigate the knowledge landscape, hot spots, and research trends in subchondral bone research through bibliometrics.Methods: Web of Science Core Collection database was used to collect articles and reviews on subchondral bone in osteoarthritis published between 2003 and 2022. CiteSpace, VOSviewer, Scimago Graphica, and a bibliometric online analysis platform (http://bibliometric.com/) were used to visualize the knowledge network of countries, institutions, authors, references, and keywords in this field. Both curve fitting and statistical plotting were performed using OriginPro, while correlation analysis was done using SPSS.Results: A total of 3,545 articles and reviews were included. The number of publications on subchondral bone showed an exponential growth trend. The US produced the most (980), followed by China (862) and the United Kingdom (364). Scientific output and gross domestic product were significantly correlated (r = .948, p < .001). The University of California System and Professor Pelletier Jean-Pierre were the most prolific institutions and influential authors, respectively. The most active and influential journal for subchondral bone research was Osteoarthritis and Cartilage. The majority of papers were financed by NSFC (474, 13.4%), followed by HHS (445, 12.6%), and NIH (438, 12.4%). In recent years, hot keywords have focused on the research of pathomechanisms (e.g., inflammation, apoptosis, pathogenesis, cartilage degeneration/repair, angiogenesis, TGF beta) and therapeutics (e.g., regeneration, stromal cell, mesenchymal stem cell).Conclusion: Subchondral bone research in osteoarthritis is flourishing. Current topics and next research trends would be centered on the pathomechanisms of cellular and molecular interactions in the subchondral bone microenvironment in the development of osteoarthritis and the exploration of targeted treatment medicines for the altered subchondral bone microenvironment.

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Bibliometric and visualization analysis of macrophages associated with osteoarthritis from 1991 to 2021

Cited by 16 publications

References 62 publications

Multi-Disciplinary Approach and Collaborative Studies Increase the Impact of Osteoarthritis Publications: A European Perspective

Multi-Disciplinary Approach and Collaborative Studies Increase the Impact of Osteoarthritis Publications: A European Perspective

Mechanisms of Peripheral and Central Sensitization in Osteoarthritis Pain

Bibliometric insights from publications on subchondral bone research in osteoarthritis

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