Bibliometric analysis of PTEN in neurodevelopment and neurodegeneration
Yun Zhang,
Ya-ting Tan,
Mei-juan Wang
et al.
Abstract:Phosphatase and tensin homologue deleted on chromosome ten (PTEN) was initially recognized as a significant regulator of cancer suppression and could impede cancer cell survival, proliferation, and energy metabolism. PTEN is highly expressed in neurons and performs crucial functions in neurogenesis, synaptogenesis, and neuronal survival. Disruption of PTEN activity may also result in abnormal neuronal function and is associated with various neurological disorders, including stroke, seizures, and autism. Althou… Show more
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