Bibliometric analysis of Helicobacter pylori resistance—from 2002 to 2022

Abstract

Background: Drug resistance in Helicobacter pylori severely affects the efficacy of eradication therapy, and a number of studies have been conducted on this issue. The aim of this study was to assess the progress in this field using a bibliometric approach. Materials and Methods:Publications related to H. pylori resistance from 2002 to 2022 were retrieved from the Web of Science database. Relevant information including titles, authors, countries, and keywords was extracted, and the data were processed using Excel, VOSviewer, and CiteSpace software for co-authorship, co-citation, and co-occurrence analysis. Results: From 2002 to 2022 (as of 09/24/2022), the field of H. pylori-resistance research produced a total of 2677 publications with a total of 75217 citations, with an overall upward trend in the annual number of articles published, reaching a peak of 204 in 2019. Articles were mainly published in Q1 or Q2 journals, with Helicobacter (TP = 261) publishing the most literature, Baylor College of Medicine (TP = 68) and Deng-chyang wu (TP = 38) being the most prolific institutions and authors, respectively. China and the United States were the locations of most of the articles, accounting for 35.08% of the global publication volume. Keyword co-occurrence analysis divided H. pylori-resistance research into four clusters: "Therapeutic Strategies," "Diseases," "Mechanism Research and Epidemiology," and "Drug Research." "Drug research" and burst detection indicate that the current research hotspot involves the selection and analysis of treatment strategies.Conclusions: H. pylori-resistance research has become a popular research field, and although there are significant contributions from Europe, the United States, and East Asia, there are significant imbalances between regions that cannot be ignored. In addition, the exploration of treatment strategies remains a key issue for research at the current stage.

Cross-talk between Helicobacter pylori and gastric cancer: a scientometric analysis

“…The WoSCC includes the most renowned and influential academic publications in natural science ( Bang et al., 2019 ; Li M. et al., 2023 ; Wang et al., 2023 ), making it an ideal data source for our research. All search results were retrieved from the WoSCC database on October 24, 2023, using the advanced search method with the keywords “Helicobacter pylori” and “stomach cancer” and their corresponding synonyms.…”

“…The Bibliometrix R package and its Web applications Biblioshiny, VOSviewer, and Microsoft Excel 2019 are used for scientometric analysis. Bibliometrix ( https://www.bibliometrix.org/ ) and VOSviewer provide a range of scientometric analysis tools for building and visualizing bibliometric networks ( Bang et al., 2019 ; Li M. et al., 2023 ; Wang et al., 2023 ). Machine learning is used to assess the distribution of various components, such as annual production, most relevant journals/authors/affiliations/countries and their local impact by H-index or total citation (TC), and annual production over time, main funding agencies, country scientific output and collaboration network, historical direct citation network, highly cited papers and high-impact factor (IF) papers, common keywords and their cluster analysis.…”

“…Bibliometrics has been effectively applied in medical research to visualize hot topics and track the evolution of knowledge in specific fields. Several studies have carried out the bibliometric analysis of HP, such as high-cited papers in HP research ( Bang et al., 2019 ), states and hotspots in HP research ( Wang et al., 2023 ) and HP resistance research ( Li M. et al., 2023 ). Over the past two decades, research on the relationship between HP and GC has steadily increased.…”

Prevalence of Clarithromycin-Resistant <i>Helicobacter pylori</i> Strains in Zambia: A Sub-Saharan African Country

“…However, their importance is still unclear [11]. Interest in H. pylori resistance is increasing with most contributions arising from Europe, the USA, and East Asia [12].…”