Biases in routine influenza surveillance indicators used to monitor infection incidence and recommendations for improvement
Oliver Eales,
James M. McCaw,
Freya M. Shearer
Abstract:BackgroundMonitoring how the incidence of influenza infections changes over time is important for quantifying the transmission dynamics and clinical severity of influenza. Infection incidence is difficult to measure directly, and hence other quantities which are more amenable to surveillance are used to monitor trends in infection levels, with the implicit assumption that they correlate with infection incidence.MethodHere we demonstrate, through mathematical reasoning, the relationship between the incidence of… Show more
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