DOI: 10.1007/3-540-32390-2_64
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Bias Field Correction for MRI Images

Abstract: Belgium. {jan. sijbers,dirk. vandyck}@ua. ac.be 3 UZ, Antwerpen, 2650 Edegem, Belgium, jan.gielen@uza.be S u m m a r y . Bias field signal is a low-frequency and very smooth signal that corrupts MRI images specially those produced by old MRI (Magnetic Resonance Imaging) machines. Image processing algorithms such as segmentation, texture analysis or classification that use the graylevel values of image pixels will not produce satisfactory results. A pre-processing step is needed to correct for the bias field si… Show more

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Cited by 81 publications
(54 citation statements)
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“…In those cases, the left breast was assessed. The density calculation was performed with 3D T1-weighted axial breast MRI images without fat saturation, using the NIH Fiji (ImageJ) image processing software, with the following steps as shown in Figure 2: 1) Image intensity bias field artefacts were corrected [31], using a 3D Gaussian filter approach to compensate for the low-frequency spatial intensity variation due to magnetic field heterogeneity prior to the segmentation process [32]; 2) Chest regions were removed from the image using a mask drawn along the pectoral muscle; 3) The breast area was cropped; 4) The entire breast was segmented using the Fiji (ImageJ) minimum/auto threshold method interactively; and 5) The bright fatty tissue was segmented using the Fiji moment/auto threshold method interactively. All the above calculations were performed throughout the entire stack of 3D breast MRI images using automated macros.…”
Section: Methodsmentioning
confidence: 99%
“…In those cases, the left breast was assessed. The density calculation was performed with 3D T1-weighted axial breast MRI images without fat saturation, using the NIH Fiji (ImageJ) image processing software, with the following steps as shown in Figure 2: 1) Image intensity bias field artefacts were corrected [31], using a 3D Gaussian filter approach to compensate for the low-frequency spatial intensity variation due to magnetic field heterogeneity prior to the segmentation process [32]; 2) Chest regions were removed from the image using a mask drawn along the pectoral muscle; 3) The breast area was cropped; 4) The entire breast was segmented using the Fiji (ImageJ) minimum/auto threshold method interactively; and 5) The bright fatty tissue was segmented using the Fiji moment/auto threshold method interactively. All the above calculations were performed throughout the entire stack of 3D breast MRI images using automated macros.…”
Section: Methodsmentioning
confidence: 99%
“…T 2 WI obtained with an ERC are often affected by bias field artifacts, which were corrected using a method described previously. 27 With this method, the bias field is first estimated from acquired image data and is later subtracted from the acquired scan. Additionally, intensity drift artifacts arising from intrapatient variability in MRI can cause image intensities to lack in tissue-specific meaning.…”
Section: Mri Preprocessingmentioning
confidence: 99%
“…The signal changes the intensity values of image pixels so that the same tissue has a different distribution of grayscale intensities across the image. 9 We applied an estimated bias field correction on the T 1 and T 2 MRIs using FMRIB Software Library (FSL) FAST ( Figure 2), 10 which will be further described in Section 2.3.…”
Section: Data Acquisitionmentioning
confidence: 99%