Bi-Modal Arterial Compliance Probe for Calibration-Free Cuffless Blood Pressure Estimation

Nabeel, P M; Joseph, Jayaraj; Karthik, Srinivasa; Sivaprakasam, Mohanasankar; Chenniappan, M

doi:10.1109/tbme.2018.2866332

Cited by 58 publications

(44 citation statements)

References 40 publications

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“…Recently, several approaches have been proposed for cuff-less BP measurement, including oscillometric finger pressing based [6], [7], ultrasound based [8], [9], pulse transit time (PTT) based [10]- [18] and multi-parameter based approaches [19]- [26]. In 2018, Chandrasekhar et al firstly proposed an oscillometric finger-pressing method for BP monitoring that can deployed on smartphone platform [6], and then developed an iPhone application with an accuracy of −4.0 ± 11.4 mmHg for systolic BP (SBP) and −9.4 ± 9.7 mmHg for diastolic BP (DBP) [7].…”

Section: Abbreviationsmentioning

confidence: 99%

Multi-Sensor Fusion Approach for Cuff-Less Blood Pressure Measurement

Miao

Liu

et al. 2020

IEEE J. Biomed. Health Inform.

106

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Ambulatory blood pressure (BP) provides valuable information for cardiovascular risk assessment. The present cuff-based devices are intrusive for longterm BP monitoring, whereas cuff-less BP measurement methods based on pulse transit time or multi-parameter are inferior in robustness and reliability by using electrocardiogram (ECG) and photoplethysmogram signals. This study examined a multi-sensor fusion-based platform and algorithm for systolic BP (SBP), mean arterial pressure (MAP), and diastolic BP (DBP) estimation. The proposed multisensor platform was comprised of one ECG sensor and two pulse pressure wave sensors for simultaneous signal collection. After extracting 35 features from the collected signals, a weakly supervised feature selection method was proposed for dimension reduction because the reference oscillometric technique-based BP are intermittent and can be redeemed as coarse-grained labels. BP models were then established using a multi-instance regression algorithm. A total of 85 participants including 17 hypertensive and 12 hypotensive patients were enrolled. Experimental results showed that the proposed approach exhibited good accuracy for diverse population with an estimation error of 1.62 ± 7.76 mmHg for SBP, 1.53 ± 6.03 mmHg for MAP, and 1.49 ± 5.52 for DBP, which complied with the association for the advancement of medical instrumentation standards in BP estimation. Moreover, the estimation accuracy is with random daily fluctuations rather than long-term degradation through a maximum two-month follow-up period indicated good robustness performance. These results suggest that the proposed approach is with high reliability and robustness and thus provides a novel insight for cuff-less BP measurement.

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Section: Abbreviationsmentioning

confidence: 99%

Multi-Sensor Fusion Approach for Cuff-Less Blood Pressure Measurement

Miao

Liu

et al. 2020

IEEE J. Biomed. Health Inform.

106

View full text Add to dashboard Cite

show abstract

“…A study on 102 healthy individuals and 37 patients affected by the vascular Ehlers-Danlos syndrome demonstrated the importance of tracing the locus of C(t) to go beyond the conventional single-value PWV to better characterize arterial pressure and stiffness changes concerning age or other collagen alterations [4]. On a similar note, we have recently developed a calibrationfree cuffless central arterial BP monitor by exploring the concept of incremental local PWV [5].…”

Section: Resultsmentioning

confidence: 99%

“…Knowing the end-diastolic and systolic peak diameter (DD and DS respectively) from D(t) for each cardiac cycle, the stiffness index β can be evaluated in a beat-by-beat manner using corresponding PS and PD values as [5]:…”

Section: Methods For Practical Implementationmentioning

confidence: 99%

“…Now, the absolute value of CD (local PWV at diastolic pressure level) corresponding to each cardiac cycle can be evaluated with the help of the proposed Pβ-model as [5]:…”

Section: Methods For Practical Implementationmentioning

confidence: 99%

“…Typically, local PWV from target arterial sites (artery under clinical investigation) is evaluated for a single and the most convenient fiduciary point from each cardiac cycle and averaged over the measurement period. Although such single-value estimates are associated with various pathophysiological conditions [1], instantaneous variation and the degree of change in local PWV within a cardiac cycle have recently been recognized as key measures for advanced cardiovascular screening and diagnosis [3][4][5]. Physiologically, the instantaneous variation in local PWV occurs due to the dependency of vessel elasticity on the arterial transmural pressure (blood pressure (BP)) [6].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Determination of Incremental Local Pulse Wave Velocity Using Arterial Diameter Waveform: Mathematical Modeling and Practical Implementation

Nabeel¹,

Raj²,

Joseph³

et al. 2019

2019 Computing in Cardiology Conference (CinC)

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Background and Aim: Given the knowledge of the noninvasive assessment of local pulse wave velocity (PWV) for cardiovascular risk stratification, it is apparent that it is necessary to develop a practically feasible solution to measure and trace instantaneous variations in local PWV (incremental local PWV) from the target arteries.Methods: From the arterial blood pulse propagation characteristics, wave nature of the transmural pressure, and the distending vessel wall geometry, a mathematical model was developed to evaluate incremental local PWV using arterial diameter waveform. Its practical feasibility and the measurement accuracy were demonstrated invivo using a custom image-free ultrasound device, with the Bramwell-Hill method as the reference.Results: The proposed technique and developed device reliably captured incremental local PWV from the carotid artery. The locus of instantaneous variations in carotid local PWV obtained using the developed model traced the reference values, with a root-mean-square-error lesser than 0.05 m/s. Study results further established the practical feasibility and accuracy of this novel approach.Conclusion: The theoretical basis and measurement method of this work is a solution for non-invasive, realtime assessment of incremental local PWV and its locus.

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MXene Functionalized, Highly Breathable and Sensitive Pressure Sensors with Multi‐Layered Porous Structure

Zheng

Zhang

Zhou

et al. 2023

Adv Funct Materials

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Breathable, flexible, and highly sensitive pressure sensors have drawn increasing attention due to their potential in wearable electronics for body‐motion monitoring, human‐machine interfaces, etc. However, current pressure sensors are usually assembled with polymer substrates or encapsulation layers, thus causing discomfort during wearing (i.e., low air/vapor permeability, mechanical mismatch) and restricting their applications. A breathable and flexible pressure sensor is reported with nonwoven fabrics as both the electrode (printed with MXene interdigitated electrode) and sensing (coated with MXene/silver nanowires) layers via a scalable screen‐printing approach. Benefiting from the multi‐layered porous structure, the sensor demonstrates good air permeability with high sensitivity (770.86–1434.89 kPa−1), a wide sensing range (0–100 kPa), fast response/recovery time (70/81 ms), and low detection limit (≈1 Pa). Particularly, this sensor can detect full‐scale human motion (i.e., small‐scale pulse beating and large‐scale walking/running) with high sensitivity, excellent cycling stability, and puncture resistance. Additionally, the sensing layer of the pressure sensor also displays superior sensitivity to humidity changes, which is verified by successfully monitoring human breathing and spoken words while wearing a sensor‐embedded mask. Given the outstanding features, this breathable sensor shows promise in the wearable electronic field for body health monitoring, sports activity detection, and disease diagnosis.

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Bi-Modal Arterial Compliance Probe for Calibration-Free Cuffless Blood Pressure Estimation

Abstract: Novel approach for calibration-free cuffless BP estimation; a potential tool for local BP measurement and hypertension screening.

Cited by 58 publications

References 40 publications

Multi-Sensor Fusion Approach for Cuff-Less Blood Pressure Measurement

Multi-Sensor Fusion Approach for Cuff-Less Blood Pressure Measurement

Determination of Incremental Local Pulse Wave Velocity Using Arterial Diameter Waveform: Mathematical Modeling and Practical Implementation

MXene Functionalized, Highly Breathable and Sensitive Pressure Sensors with Multi‐Layered Porous Structure

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