Bi-caval dual lumen venovenous extracorporeal membrane oxygenation and high-frequency percussive ventilatory support for postintubation tracheal injury and acute respiratory distress syndrome

Fitzgerald, Julie C.; Topjian, Alexis; McInnes, Andrew D.; Mattei, Peter; McCloskey, John; Friess, Stuart H.; Kilbaugh, Todd J.

doi:10.1016/j.jpedsurg.2011.09.048

Cited by 11 publications

(7 citation statements)

References 18 publications

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“…neuromuscular blockade, iNO, prone ventilation, and HFOV), making salvage therapy comparisons for severe ARDS difficult to interpret. [2][3][4][5] Based on available data, overall survival for ECMO varies from 44% to 79% in trauma. 6,7 Compared to severe respiratory failure in the uninjured population, trauma ECMO survival rates may be higher than non-trauma ECMO survival rates.…”

Section: Discussionmentioning

confidence: 99%

Extracorporeal membrane oxygenation in trauma: A single institution experience and review of the literature

et al. 2018

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Section: Discussionmentioning

confidence: 99%

Extracorporeal membrane oxygenation in trauma: A single institution experience and review of the literature

et al. 2018

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“…Similarly, human metapneumovirus (HMP) infection has been associated with hospitalization and morbidity in children, and is a cause of bronchiolitis and pneumonia . ARDS associated with HMP has been described in case reports and a cohort study, and findings suggest that HMP infection in some children may be as severe as RSV infection . Risk factors for severe HMP or RSV infection include age <6 months and a history of prematurity .…”

Section: Introductionmentioning

confidence: 99%

Pediatric acute respiratory distress syndrome associated with human metapneumovirus and respiratory syncytial virus

Ravindranath

Gomez

Harwayne‐Gidansky

et al. 2018

Pediatric Pulmonology

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“…Pulmonary surfactant is observed after 28 weeks gestation, meaning that premature children are vulnerable to ALI and the further development and maturation are affected. A lower gestational age is associated with an increased risk of lung damage (7,8).…”

Section: Introductionmentioning

confidence: 99%

Allicin attenuates lipopolysaccharide‑induced acute lung injury in neonatal rats via the PI3K/Akt pathway

et al. 2018

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Allicin is an oxygenated carotenoid derivative that exhibits strong antioxidant activity, which effectively removes reactive oxygen species from the body and has important roles in disease prevention and treatment. Therefore, the present study aimed to investigate whether allicin attenuates lipopolysaccharide (LPS)‑induced acute lung injury (ALI) in neonatal rats and the potential underlying mechanisms. An LPS‑induced ALI neonatal rat model was utilized to assess the therapeutic value and mechanisms of allicin. Following allicin treatment, increases in lung wet/dry ratio and the lung protein concentration were significantly suppressed in LPS‑induced ALI neonatal rats. Furthermore, ELISA results demonstrated that allicin significantly reduced the levels of malondialdehyde, tumor necrosis factor‑α and interleukin‑6, and increased superoxide dismutase activity, in the bronchoalveolar lavage fluid of LPS‑treated rats. Additionally, allicin administration increased the protein expression of Bcl‑2 and reduced the activity of caspase‑3/-9, as determined by western blotting or ELISA, respectively, and increased phosphatidylinositol 3‑kinase (PI3K) and phosphorylated‑Akt protein levels, in LPS‑treated ALI neonatal rats. The results of the present study indicate that allicin attenuate LPS‑induced ALI in neonatal rats by ameliorating oxidative stress, inflammation and apoptosis via the PI3K/Akt pathway. Allicin may be used for development of a novel drug for treatment of ALI.

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Bi-caval dual lumen venovenous extracorporeal membrane oxygenation and high-frequency percussive ventilatory support for postintubation tracheal injury and acute respiratory distress syndrome

Cited by 11 publications

References 18 publications

Extracorporeal membrane oxygenation in trauma: A single institution experience and review of the literature

Extracorporeal membrane oxygenation in trauma: A single institution experience and review of the literature

Pediatric acute respiratory distress syndrome associated with human metapneumovirus and respiratory syncytial virus

Allicin attenuates lipopolysaccharide‑induced acute lung injury in neonatal rats via the PI3K/Akt pathway

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