Beyond the lymph nodes: FDG-PET/CT in primary extranodal lymphoma

Beyond lymph nodes: 18F-FDG PET/CT in detection of unusual sites of extranodal lymphoma

“…Four (4%) were primary lymphoma (3% NHL and 1% HD), and 11% were secondary lymphoma (10% NHL and 1% HD). These findings were in agreement with Sin et al [1] who reported that secondary GIT lymphoma is relatively common while primary small bowel lymphoma is rare. Gastric lymphoma was found in 8% of cases (7% NHL seen as diffuse mural thickening and 1% HD seen as exophytic masses) (Fig.…”

“…Thyroid gland lymphoma was depicted in 2% of cases (1% secondary and 1% primary). The important differential is anaplastic carcinoma which has strong avidity to FDG and heterogeneous enhancement in diagnostic CT [1]. According to Sin et al [1], diffuse but low-grade thyroid FDG uptake can be seen in other non-lymphomatous conditions such as reactive uptake, Hashimoto thyroiditis, and post-chemotherapy.…”

“…Lymphoma is a malignancy that originates from the lymphatic system but can occur at extranodal sites [1]. Extranodal disease is commonly part of lymphomatous involvement (secondary lymphoma), but it can also be the primary site where lymphoma arises (primary lymphoma) [2].…”

Combined positron emission tomography/computed tomography for diagnosis and monitoring of orbital adnexal lymphoma

“…; Sin et al. ). For orbital and OAL, use of PET/CT has been proven to be feasible and is now accepted both as a standard part of the initial staging work‐up and for the assessment of response to therapy (Hui et al.…”

“…For the OAL patients included in this study, combined whole-body PET/CT proved to be a sensitive imaging modality for initial staging as well as therapy monitoring of OAL enabling both accurate morphological and metabolic evaluation. FDG PET/CT seems to be of particular benefit for the assessment of extranodal lymphoid tissue (Johnson et al 2015;Sin et al 2017). For orbital and OAL, use of PET/CT has been proven to be feasible and is now accepted both as a standard part of the initial staging work-up and for the assessment of response to therapy (Hui et al 2012).…”