Beyond the Gut: The intratumoral microbiome's influence on tumorigenesis and treatment response
Hao Zhang,
Li Fu,
Xinwen Leiliang
et al.
Abstract:The intratumoral microbiome (TM) refers to the microorganisms in the tumor tissues, including bacteria, fungi, viruses, and so on, and is distinct from the gut microbiome and circulating microbiota. TM is strongly associated with tumorigenesis, progression, metastasis, and response to therapy. This paper highlights the current status of TM. Tract sources, adjacent normal tissue, circulatory system, and concomitant tumor co‐metastasis are the main origin of TM. The advanced techniques in TM analysis are compreh… Show more
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