Beyond resection boundaries for glioblastoma patients: is “primum non nocere” a key factor for prognosis?
Andrea Cristofori,
Chiara Benedetta Rui,
Francesca Graziano
et al.
Abstract:Purpose
Maximal resection has a pivotal role in the treatment of glioblastoma, prolonging both progression free survival (PFS) and overall survival (OS). Increasingly, very few studies analyze the delicate equilibrium between maximal resection, clinical outcome and prognosis. The aim of this study is to determine the impact of neurological impairment on PFS, OS and access to adjuvant therapies.
Methods
this retrospective study encompassed patients operated for a GBM at Fondazione IRCCS San Gerardo dei Tintor… Show more
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