The existence of quantum droplets in binary Bose-Einstein condensate mixtures rely on beyondmean field effects, competing with mean-field-effects. Interestingly, the beyond-mean field effects change from repulsive in three dimension (3D) to attractive in 1D leading to drastically different behaviors. We quantitatively model quantum droplets in the beyond-mean-field crossover from 1D to 3D in the relevant case of an elongated harmonic trap and give realistic numbers for experimental realizations. We identify and quantify two main limiting factors: three-body losses and tiny energy scales. The crossover region is appealing as it offers a trade-off between these two main limitations opening the possibility of observing stable flat-top density profiles, a yet unobserved, characteristic feature of quantum droplets. It would permit testing beyond-mean-field theories to an unprecedented precision.