Beyond graphene: Electrochemical sensors and biosensors for biomarkers detection

Bollella, Paolo; Fusco, Giovanni; Tortolini, Cristina; Sanzò, Gabriella; Favero, Gabriele; Gorton, Lo; Antiochia, Riccarda

doi:10.1016/j.bios.2016.03.068

Cited by 333 publications

(210 citation statements)

References 80 publications

Supporting

Mentioning

207

Contrasting

Unclassified

Order By: Relevance

“…However, the conductivity of single flakes, the average thickness after reduction, and the structural quality of microbially‐reduced graphene oxide (mrGO) have not yet been determined, making it impossible to identify the feasibility of the microbial production approach and the range of potential applications for reduced graphene oxide produced through this method. A high conductance and surface‐to‐volume ratio would make mrGO applicable to field effect transistors (FET), biosensors, transparent conductors, batteries, graphene polymer nanocomposites, and conductive inks …”

Section: Introductionmentioning

confidence: 99%

Creation of Conductive Graphene Materials by Bacterial Reduction Using Shewanella Oneidensis

et al. 2019

View full text Add to dashboard Cite

Graphene's maximized surface‐to‐volume ratio, high conductance, mechanical strength, and flexibility make it a promising nanomaterial. However, large‐scale graphene production is typically cost‐intensive. This manuscript describes a microbial reduction approach for producing graphene that utilizes the bacterium Shewanella oneidensis in combination with modern nanotechnology to enable a low‐cost, large‐scale production method. The bacterial reduction approach presented in this paper increases the conductance of single graphene oxide flakes as well as bulk graphene oxide sheets by 2.1 to 2.7 orders of magnitude respectively while simultaneously retaining a high surface‐area‐to‐thickness ratio. Shewanella ‐mediated reduction was employed in conjunction with electron‐beam lithography to reduce one surface of individual graphene oxide flakes. This methodology yielded conducting flakes with differing functionalization on the top and bottom faces. Therefore, microbial reduction of graphene oxide enables the development and up‐scaling of new types of graphene‐based materials and devices with a variety of applications including nano‐composites, conductive inks, and biosensors, while avoiding usage of hazardous, environmentally‐unfriendly chemicals.

show abstract

Section: Introductionmentioning

confidence: 99%

Creation of Conductive Graphene Materials by Bacterial Reduction Using Shewanella Oneidensis

et al. 2019

View full text Add to dashboard Cite

show abstract

“…However, the graphene is known as the first two‐dimensional structure in the world. Recently, it has been recognized as one of the most sought‐after 2D layered nanomaterial with its superior performance and potential application . Graphene production techniques have been known mechanical cleavage, chemical peeling, epitaxial growth, Hummers method, sublimation of 4HSiC, electrochemical reduction, and CVD .…”

Section: Introductionmentioning

confidence: 99%

Few‐layer graphene coated on indium tin oxide electrodes prepared by chemical vapor deposition and their enhanced glucose electrooxidation activity

2019

View full text Add to dashboard Cite

At present, few‐layer graphene is deposited on copper (Cu) foil by chemical vapor deposition (CVD) method. Then, the few‐layer graphenes produced on the Cu foil are coated onto the indium tin oxide (ITO) electrode to investigate their glucose electrooxidation activities. Hexane and hydrogen flow rate and deposition time parameters with CVD method are examined on different Cu foils. These electrodes are characterized by scanning electron microscopy‐energy dispersive X‐ray analysis (SEM‐EDX), X‐ray photoelectron spectroscopy (XPS), and Raman spectroscopy. Furthermore, glucose electrooxidation is examined with cyclic voltammetry (CV), chronoamperometry (CA), and electrochemical impedance spectroscopy (EIS) measurements. One could note that the graphene network is clearly visible from SEM images. The deconvoluted XPS spectrum indicates that carbon appeared in the form of non‐oxygenated ring C atoms for few‐layer graphene. The few‐layer graphene structure is confirmed by Raman analysis. Few‐layer graphene/ITO produced at 5 sccm Hexane and 50 sccm hydrogen flow rate and 20 minutes deposition time (G7/ITO) reveals the best electrode activity. The specific activity of G7/ITO electrode is obtained as 6.58 mA cm−2. According to CV, CA, and EIS results, G7/ITO electrode has high electrocatalytic activity, stability, and resistance in comparison with other electrodes.

show abstract

“…This is favourable for a wide spectrum of diverse applications. Further, after exposure to air or water, it degrades to nontoxic phosphorus intermediates as P x O y , thus is considered to be biodegradable . Prospective introduction of BP in industrial applications and in the area of biomedicine are holding huge potential.…”

Section: Introductionmentioning

confidence: 99%

Black Phosphorus Cytotoxicity Assessments Pitfalls: Advantages and Disadvantages of Metabolic and Morphological Assays

Fojtů

Raudenská

Vičar

et al. 2018

Chemistry A European J

View full text Add to dashboard Cite

Black phosphorus (BP) belongs to a group of 2D nanomaterials and nowadays attracts constantly increasing attention. Parallel to the growing utilization of BP nanomaterial increase also the requirements for the thorough comprehension of its potential impact on human and animal health. The aim of this study was to compare and discuss five assays commonly used for the cytotoxicity assessments of nanomaterials with a special focus on BP nanoparticles. A comprehensive survey of factors and pitfalls is provided that should be accounted for when assessing their toxicity and pointed to their inconsistency. BP might introduce various levels of interference during toxicity assessments depending on its concentration applied. More importantly, the BP toxicity evaluation was found to be influenced by the nature of assay chosen. These are based on different principles and do not have to assess all the cellular events equally. A commercial assay based on the measurement of protease activity was identified to be the most suitable for the BP toxicity assessment. Further, the benefit of time‐lapse quantitative phase imaging for nanomaterial toxicity evaluation was highlighted. Unlike the conventional assessments it provides real‐time analysis of the processes accompanying BP administration and enables to understand them deeper and in the context.

show abstract

Beyond graphene: Electrochemical sensors and biosensors for biomarkers detection

Cited by 333 publications

References 80 publications

Creation of Conductive Graphene Materials by Bacterial Reduction Using Shewanella Oneidensis

Creation of Conductive Graphene Materials by Bacterial Reduction Using Shewanella Oneidensis

Few‐layer graphene coated on indium tin oxide electrodes prepared by chemical vapor deposition and their enhanced glucose electrooxidation activity

Black Phosphorus Cytotoxicity Assessments Pitfalls: Advantages and Disadvantages of Metabolic and Morphological Assays

Contact Info

Product

Resources

About