Beyond Fear: Posttraumatic Stress Disorder Patients Fail to Engage in Safety Cues

Stress and the brain: Emotional support mediates the association between myelination in the right supramarginal gyrus and perceived chronic stress

“… Kogler et al (2015) conducted a meta-analysis of neuroimaging studies and identified the SMG as a key brain region activated during physiological stress. Patients with PTSD were shown to have alterations in neural activity and functional connectivity of the SMG as compared to healthy controls ( Bastos et al, 2022 ; Dossi et al, 2020 ; Felmingham et al, 2009 ; Rabellino et al, 2018 ). In addition, preliminary evidence has suggested that the associations of ICM with cognitive function may be through its importance for the integrity of neural connections and neural synchrony of cerebral cortex, particularly the facilitation of local brain synchrony ( Grydeland et al, 2016 ; Vandewouw et al, 2021 ; Yang et al, 2020 ).…”