Bewertung verschiedener Methoden des Schmerzmanagements
                    während der Behandlung von Klauenlederhaut-Läsionen bei weiblichen
                    Merinofleischschafen

Fieseler, H; Weck, Romy; Kaiser, Matthias J.; Müller, Hendrik; Spilke, Joachim; Mielenz, N.; Möbius, G; Starke, Alexander

doi:10.1055/a-0947-8428

Cited by 2 publications

(2 citation statements)

References 35 publications

(47 reference statements)

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“…In the study of Fieseler et al (2019) the moving of the head appeared to be primarily stress-related in association with dorsal recumbency. Furthermore, Sanhouri et al (1992) describe a decrease in flighting behavior during the transportation of male goats under the influence of xylazine.…”

Section: Treatment Effectmentioning

confidence: 92%

“…A similar study setup as in Fieseler et al (2018Fieseler et al ( , 2019 and Heinrich et al (2020) was chosen (Figure 1). On day -2, a permanent residing catheter was inserted in the jugular vein in a priorly shaved, alcohol and iodine disinfected, and anesthetized [2-3 ml 2% Isocaine subcutaneous (s.c.)] location in the middle third of the lateral side of the neck.…”

Section: Study Design and Proceduresmentioning

confidence: 99%

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Sedation With Xylazine Hydrochloride Decreases the Stress Response in Merino Meat Sheep During Routine Hoof Trimming in a Tilt Table

et al. 2022

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We hypothesized that the hoof trimming in sheep in dorsal recumbency implicates a short but intensive stress situation and that the sedation with xylazine causes a decrease in the stress response in this situation. Ten healthy female merino meat sheep were randomly divided into two groups receiving either xylazine hydrochloride (0.1 mg/kg body mass (BM) applied intramuscularly) or a placebo treatment with 0.9% NaCl. Routine hoof trimming was performed in a tilt table and vital signs (rectal temperature (RT), heart rate (HR), and respiratory rate (RR)), 33 different behavioral traits and blood cortisol concentrations were recorded throughout the experiment at six different time points (total of 55 min). The procedure itself elicited a clear stress response (increase in the RR, RT, defensive movements, lip twitching, swallowing, and flight behavior). Parallelly, the blood cortisol concentrations were increased, reaching their maximum with 81.5 ng/ml in the control group when the sheep were tilted back into a standing position. In the sedated sheep, no increase in the RR and RT and a decrease in the HR were observed. In addition, the behavioral signs showed a decrease in flight, defensive, and general stress behavior (decrease in licking, movement of head and legs, and sitting on knees), complemented by the serum cortisol concentrations showing 2.28 times reduced concentration at the end of the procedure, compared to the control sheep. The results confirm our hypothesis and support the conduction of future trials investigating the feasibility and benefit of a sedation of sheep prior to routine hoof trimming under practical circumstances.

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Section: Treatment Effectmentioning

confidence: 92%

Section: Study Design and Proceduresmentioning

confidence: 99%

Sedation With Xylazine Hydrochloride Decreases the Stress Response in Merino Meat Sheep During Routine Hoof Trimming in a Tilt Table

et al. 2022

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Effect of a targeted pain management protocol for the treatment of dermatitis interdigitalis contagiosa in Merino meat sheep in a tilt squeeze chute

Rachidi¹,

Wagner²,

Fieseler³

et al. 2022

Front. Anim. Sci.

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IntroductionThe effect of a targeted pain management protocol consisting of sedation and local anesthesia on the stress response to treatment of dermatitis interdigitalis contagiosa (DINCO) was assessed in sheep placed in dorsal recumbency.MethodsBlood cortisol concentrations were measured once a day (Day -3 to 2) and additionally on day 0, six times during the claw treatment (stress model). Twelve healthy sheep (control group; HEALTHY) and 36 sheep with DINCO, randomly allocated to one of three treatment groups, underwent the stress model with or without pain control: the XYLA-IVRA sheep were sedated with 2% xylazine hydrochloride (XYLA) and received retrograde intravenous regional anesthesia (IVRA); the IVRA sheep underwent IVRA and received a placebo instead of sedation; the PLACEBO sheep received placebos for sedation and IVRA. The HEALTHY sheep underwent sham claw treatment and received placebos.Results and discussionThe cortisol concentrations were higher in sheep restrained in dorsal recumbency compared with the cortisol concentrations measured four hours later in standing sheep (HEALTHY 37.2 ± 3.3 ng/ml vs. 18.5 ± 3.3 ng/ml; DISEASED 34.0 ± 1.9 ng/ml vs. 17.6 ± 1.9 ng/ml; p < 0.001). The stress response of XYLA-IVRA (area under the curve; AUC = 34.9 ± 2.6 ng/ml) was reduced compared with the stress response of PLACEBO (AUC = 48.0 ± 2.6 ng/ml, p < 0.01) and HEALTHY sheep (AUC = 46.6 ± 2.5 ng/ml; p = 0.01). While cortisol concentration of XYLA-IVRA and HEALTHY sheep did not increase one day after the stress model (Day 1) compared with the day of the stress model (Day 0), both PLACEBO (47.4 ± 3.3 vs. 35.6 ± 3.1 ng/ml, p = 0.02) and IVRA sheep (39.1 ± 2.8 vs. 28.6 ± 3.1 ng/ml, p = 0.01) had higher cortisol concentrations. The results confirm that fixation in dorsal recumbency in a tilt squeeze chute was a major stressor in sheep. The differences in the cortisol concentration of the PLACEBO sheep versus the XYLA-IVRA sheep during and after the stress model illustrate the effect and necessity of pain management protocols in practice.

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Bewertung verschiedener Methoden des Schmerzmanagements während der Behandlung von Klauenlederhaut-Läsionen bei weiblichen Merinofleischschafen

Cited by 2 publications

References 35 publications

Sedation With Xylazine Hydrochloride Decreases the Stress Response in Merino Meat Sheep During Routine Hoof Trimming in a Tilt Table

Sedation With Xylazine Hydrochloride Decreases the Stress Response in Merino Meat Sheep During Routine Hoof Trimming in a Tilt Table

Effect of a targeted pain management protocol for the treatment of dermatitis interdigitalis contagiosa in Merino meat sheep in a tilt squeeze chute

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