Between China and Italy: A case report of first-episode schizophrenia in the Covid-19 era

Murri, Martino Belvederi; Zotos, Spyridon; Cantarelli, Luca; Berardi, Lorenzo; Curtarello, Eleonora Maria Alfonsina; Folesani, Federica; Gullotta, Benedetta; Bertolini, Enrica; Girotto, Barbara; Carozza, Paola; Grassi, Luigi

doi:10.1016/j.psychres.2021.113804

Cited by 3 publications

(2 citation statements)

References 2 publications

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“…During the COVID-19 lockdown, psychiatric disorders increased by 6.8 %, with schizophrenia and acute transitional psychosis being particularly prominent ( Jagadheesan et al, 2021 ). Recent two case reports also revealed that people with no history of psychiatric condition developed psychotic symptoms during COVID-19 lockdown ( Belvederi Murri et al, 2021 ; Oloniniyi et al, 2021 ). However, most studies focus on the pandemic's impact on psychiatric patients or the symptoms of psychosis in people infected with the virus ( Brown et al, 2020 ), related research among the general population is sparse.…”

Section: Introductionmentioning

confidence: 99%

Psychotic-like experiences during COVID-19 lockdown among adolescents: Prevalence, risk and protective factors

Wang

Zhou

Chen

et al. 2023

Schizophrenia Research

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Section: Introductionmentioning

confidence: 99%

Psychotic-like experiences during COVID-19 lockdown among adolescents: Prevalence, risk and protective factors

Wang

Zhou

Chen

et al. 2023

Schizophrenia Research

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“…During the COVID-19 outbreak, two patients with no history of psychiatric disease acquired COVID-19-related delusional themes and unusual behaviors, according to a case report (Oloniniyi et al, 2021 ). Another case report revealed that a 19-year-old Chinese-American student developed schizophrenia for the first time during a lockdown, implying that social isolation has a particular impact on individuals (Belvederi Murri et al, 2021 ). Mental diseases increased by 6.8% during COVID-19 lockdown, according to a cross-sectional study by Karuppiah et al, with schizophrenia and acute transitory psychosis being particularly prominent (Jagadheesan et al, 2021 ).…”

mentioning

confidence: 99%

Risk of First-Episode Schizophrenia in Aged Adults Increased During COVID-19 Outbreak

et al. 2021

Int J Ment Health Addiction

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We noticed an unusual increase of aged adults in first-episode schizophrenia in January and February 2020 since the outbreak of COVID-19. This retrospective study aims to statistically validate this observation and find potential risk factors, if applicable. The demographics of schizophrenia in outpatients (both first-episode and follow-up) from January to March 2020 (36,624 records) and similar periods of 2017–2019 (114,141 records) were analyzed and compared to minimize seasonal influence. Limited personal information (age, gender, approximate residence) was investigated to find risk factors. After considering seasonal factors such as the Spring festival, the age of the first-episode schizophrenia was significantly increased in January (46.60 ± 15.14) and February (51.53 ± 14.74) but went back to normal in March 2020 (38.89 ± 14.59), compared with similar periods from 2017 to 2019 (Jan., 40.77 ± 15.26; Feb., 39.69 ± 15.10; Mar., 42.04 ± 15.83). Meanwhile, a slight but not significant change was found in the distribution of gender and approximate residence (urban/suburb). Our data supported that risk of first-episode schizophrenia in aged adults increased during the COVID-19 outbreak, which is consistent with the fact that COVID-19 is more lethal to elders. Public healthcare should prepare in advance for potential risks in public mental health, especially for elders.

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First-episode psychotic disorders in the wake of the COVID-19 pandemic: a descriptive review of casereports

Rittmannsberger¹,

Barth²,

Malík³

et al. 2022

Acta Neuropsychiatr.

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Objective: Since the onset of COVID-19 pandemic many case reports and case series dealt with new onset psychotic disorders in patients either infected with SARS-CoV-2 or thematically linked to the pandemic, but without an infection. Our aim was to provide a comprehensive collection of these reports to illustrate the nature of these psychoses. Methods: We conducted a literature search in Medline, EMBASE, PSYCHINFO, using search terms regarding first episode psychotic disorders in the context of corona. Results: 96 case reports or case series covering 146 patients (62 without and 84 with SARS-CoV-2 infection) were found. Compared to patients without infection, patients with infection showed significantly more often visual hallucinations (28.6% vs 8.1%), confusion (36.9% vs 11.3%), an acute onset of illness (88.5% vs 59.6%) and less often depression (13.1% vs 35.5%) and a delusional content related to the pandemic (29.5% vs 78.3%). Both groups had an equally favourable outcome with a duration of psychosis ≤2 weeks in half and full remission in two thirds of patients. In patients with infection signs of inflammation were reported in 78.3% and increased CRP in 58.6%. While reports on patients with infection are continuously published, no report about patients without infection was found after July 2020. Conclusion: Cases without infection were considered reactive and originated all from the first wave of the Corona pandemic. In cases with infection, inflammation was considered as the main pathogenetic factor but was not found in all patients. Diagnosis was impeded by the overlap of psychosis with delirium.

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Between China and Italy: A case report of first-episode schizophrenia in the Covid-19 era

Cited by 3 publications

References 2 publications

Psychotic-like experiences during COVID-19 lockdown among adolescents: Prevalence, risk and protective factors

Psychotic-like experiences during COVID-19 lockdown among adolescents: Prevalence, risk and protective factors

Risk of First-Episode Schizophrenia in Aged Adults Increased During COVID-19 Outbreak

First-episode psychotic disorders in the wake of the COVID-19 pandemic: a descriptive review of casereports

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