Betulin-3-Caffeate from Quercus suber, ¹³C-nmr Spectra of Some Lupenes

Betulinic Acid Inhibits LPS-Induced MMP-9 Expression by Suppressing NF-kB Activation in BV2 Microglial Cells

“…Betulinic acid was isolated from n-hexane fraction using silica gel column chromatography. The chemical structure of the compound was determined by means of 1 H-NMR (600 MHz) and EI-MS and identifi ed to betulinc acid by comparison with spectral data from the literature (Patra et al, 1988;Do et al, 1991). The compound was dissolved in ethanol and added to the cell culture at the desired concentrations.…”

Seven New Phenolic Glucosides from Viburnum cylindricum

“…for corresponding formulas) were identified as henryoside (8) [9], O-hydroxybenzyl salicylate [12], salicyloylsalicin [12], (þ)-licarin A [13], 3,22-dihydroxyolean-12-en-25-al [14], (2a,3b)-olean-12-ene-2,3-diol [15], 6-hydroxy-3-oxoolean-12-en-28-oic acid [16], ovalifoliogenin [17], ursomyricerone [18], olean-12-ene-2,3,22-triol [19], maniladiol [20], crategolic acid [21], camaldulensic acid [22], masticadienic acid [23], betulinic acid [24], alismoxide [8], 3,3',4',7-tetrahydroxyflavone [25], apigenin [26], 3,4-dimethylbenzoic acid [27], 4-hydroxybenzoic acid [28], 2H-1-benzopyran-2-one [29], umbelliferone [30], aesculetin [31], gallic acid [32], 3,5-dihydroxybenzoic acid methyl ester [33], and 3,5-dihydroxybenzoic acid [32] on the basis of their NMR data and by comparison with the literature data. To the Table 3.…”

Synthesis of betulonic acid amides

“…PMR and 13 C NMR spectra of 2a-n, 3, and 4 agreed completely with their structures. Resonances of H and C atoms in NMR spectra of 2a-n, 3, and 4 were assigned based on two-dimensional NMR spectra of 2d, f, g, i, m, and 4 using literature data for betulonic acid and its amino-acid derivatives [9,10]. We verified the resonances for H-2′ (8.23 ppm) and H-4′ (7.00 ppm) (protons of the imidazole ring) of 2m, for which chemical shifts at 7.01 and 8.25 ppm, respectively, were assigned [11].…”