Better Weight Loss, Resolution of Diabetes, and Quality of Life for Laparoscopic Gastric Bypass vs Banding

Campos, Guilherme M.; Rabl, Charlotte; Roll, Garrett R.; Peeva, Sofia; Prado, Kris; Smith, Jessica; Vittinghoff, Eric

doi:10.1001/archsurg.2010.316

Cited by 69 publications

(45 citation statements)

References 51 publications

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“…Resolution of diabetes was observed in 78% of the patients treated with Roux-en-Y gastric bypass who had diabetes before surgery, compared with 50% resolution in previously diabetic patients who received laparoscopic adjustable gastric banding. In a recent 2 cohort pair matched study of 200 obese patients, diabetes resolution occurred in 76% of patients who underwent RYGB compared with 50% of those who had LAGB [29]. Lee et al [30] have published the results of a RCT comparing gastric bypass versus sleeve gastrectomy in patients with BMI 25-35 kg/m 2 ; the remission rate for T2DM was 93% for patients who underwent RYGB compared with 47% for those who underwent sleeve gastrectomy.…”

Section: Comparative Efficacy Of Different Bariatric Proceduresmentioning

confidence: 99%

Surgical treatment of type 2 diabetes: the surgeon perspective

et al. 2011

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Type 2 diabetes mellitus (T2DM) is a major health priority globally, having achieved pandemic status in the twenty-first century. Several gastrointestinal procedures that were primarily designed to treat morbid obesity result in dramatic remission of diabetes. Studies in experimental rodent models and humans have shown that the glycemic benefits of surgery are at least in part weight-independent and extend to non-morbidly obese subjects with T2DM. Bariatric procedures differ in their ability to ameliorate type 2 diabetes, with intestinal bypass procedures being more effective than purely restrictive procedures. Several studies have demonstrated that the benefits of bariatric surgery extend beyond amelioration of hyperglycemia and include improvement in other cardiovascular risk factors such as dyslipidemia and hypertension. The safety and cost-effectiveness of bariatric surgery are also well established by several studies. In this paper, the authors present the surgeon perspective on the management of type 2 diabetes focusing on the efficacy, safety and cost-effectiveness of metabolic surgery. The available evidence warrants the inclusion of metabolic surgery in the treatment algorithm of type 2 diabetes.

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Section: Comparative Efficacy Of Different Bariatric Proceduresmentioning

confidence: 99%

Surgical treatment of type 2 diabetes: the surgeon perspective

et al. 2011

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“…A study of adults by Campos et al 66 found that RYGB had a higher rate of early complications (11% vs 2%) but that LAGB had a significantly increased rate of late complications with reoperation occurring much more frequently (13% vs 2%). More concerning are 2 prospective studies 67,68 from Europe of long-term outcomes after placement of the LAGB.…”

Section: Laparoscopic Adjustable Gastric Bandingmentioning

confidence: 99%

Adolescent Bariatric Surgery

Hsia¹,

Fallon²,

Brandt³

2012

Arch Pediatr Adolesc Med

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“…A prospective two-cohort pair-matched study by Campos et al, compared 100 LAGB patients to 100 RYGB patients [18]. Preoperatively the mean BMI was 45.7 kg/m 2 in the LAGB group and 46.0 kg/m 2 in the RYGB.…”

Section: Malabsorptive Versus Restrictive Proceduresmentioning

confidence: 99%

Treatment of obesity and diabetes with bariatric surgery

Whitlock¹,

Gill²,

Switzers³

et al. 2013

Glob Epidemi Obes

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Obesity rates are on the rise worldwide. Nearly 1 in every 4 Canadians is classified as being overweight. With an increase in obesity, there is also a correlated rise in its comorbidities, most notably Type-2 Diabetes Mellitus (T2DM). Bariatric surgery is superior to diet and lifestyle management in managing the severe obese. These bariatric procedures are traditionally classified as either being restrictive(reducing caloric intake), or malabsorptive (re-routing the gastrointestinal tract). The roux-en-Y gastric bypass (RYGB) is the most commonly performed bariatric surgery. Studies have shown that post-RYGB, there is a significant improvement or even complete resolution in patients' type-2 diabetes mellitus (T2DM), with significantly more patients achieving euglycemia compared to the control population. RYGB has also been shown to prevent the development of T2DM. When RYGB was compared to more restrictive procedures, it achieved superior results in both weight-loss and T2DM resolution and the maintenance of these results long-term. The superiority of procedures, such as RYGB, is potentially explained through alterations in gut hormones, ghrelin and GLP-1. In this review, we explore the role of bariatric surgery in the prevention and treatment of T2DM, with a specific focus on the recent evidence surrounding surgical treatment via RYGB.

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Better Weight Loss, Resolution of Diabetes, and Quality of Life for Laparoscopic Gastric Bypass vs Banding

Cited by 69 publications

References 51 publications

Surgical treatment of type 2 diabetes: the surgeon perspective

Surgical treatment of type 2 diabetes: the surgeon perspective

Adolescent Bariatric Surgery

Treatment of obesity and diabetes with bariatric surgery

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