Better Results in Facial Rejuvenation with Fillers

Abstract

Summary: Facial rejuvenation is a rapidly advancing field in aesthetic medicine. Minimally invasive techniques represent a powerful tool for rejuvenation, and fillers are a popular modality with which to restore and optimize facial proportions. Currently, our filler armamentarium is characterized by products with an increasing variety of biochemical compositions warranting tailored injection approaches. An intimate knowledge of anatomy, product characteristics, and appropriate injection techniques is essential to achieve optimal results while maintaining patient safety. Here, we review facial anatomy, structural changes secondary to aging, appropriate filler selection, safe injection techniques, and complications.

In vivoinducing collagen regeneration of biodegradable polymer microspheres

“…Dermal fillers specialize in repairing soft tissue volume loss and deep static wrinkles or folds, having advantages of simple operation, small trauma, short recovery time and obvious repair effect, etc. [ 1 , 2 ] When compared with traditional dermal fillers that only have functions of replacement or filling, the new-generation dermal fillers like Sculptra ® , whose main ingredient is poly (L-lactic acid) (PLLA) microspheres, has biological stimulation effect to stimulate the regeneration of endogenous collagen and dermal fibrocytes after injection [ 3 , 4 ]. The effect of PLLA microspheres on deep wrinkles or folds such as crow’s feet, nasolabial furrows and puppet strings is significant and could maintain for 18–25 months [ 5 ], and on forearm area could even over 28 months [ 6 ].…”

Validating a Series of Photonumeric Rating Scales for Use in Facial Aesthetics Using Statistical Analysis of Intra- and Inter-rater Reliability

“…Demand for minimally invasive aesthetic procedures that aim to correct age-related changes and optimize facial proportions, such as dermal fillers and botulinum toxin, has increased dramatically over the last 2 decades. 1 , 2 To meet this demand, companies within the aesthetic space have sought to develop innovative technologies to assist in facial rejuvenation, and the number of devices and treatments continues to grow. With this growth comes a need for objective assessment of treatment results and, therefore, development of tools for evidence-based evaluation of new techniques for a range of anatomical areas.…”

“…While aging causes predictable changes in soft tissue, fat, and bone, these changes depend on variations in both intrinsic and extrinsic variables, such as genetics, ethnicity, and sun exposure. 2 , 5 To date, few rating scales have been developed and validated to measure each area of the face objectively and are somewhat lacking for jawline contour and temple hollowing. 5-11 …”

“… 12 Additionally, nasolabial folds, pre-jowl sulci, and jowls become more pronounced, and skin and soft tissue laxity can compound the descent of facial features arising from atrophy and the age-related recession of the jaw, chin, and cheeks. 2 , 12 …”

“…The ideal jawline is free of sulci or excess/sagging skin, well-defined, and smooth along the angle of the mandible until the chin, which balances the lower face—accordingly, adequate chin projection, straightness, and size influence facial beauty. 2 , 6 , 12 Lip shape and fullness also contribute to an aesthetically youthful appearance, and age-related volume loss results in flattening, shrinking, and fading of the lips and can worsen the appearance of perioral lines. 12 , 13 On the upper face, the ideal forehead has a gentle convex curve with flat temples free of any depressions and hollowing.…”