Better Rejection‐Free Survival at Three Years in Kidney Transplant Recipients With Model‐Informed Precision Dosing of Mycophenolate Mofetil
Claire Villeneuve,
Antoine Humeau,
Caroline Monchaud
et al.
Abstract:The clinical impact of individual dose adjustment of mycophenolate mofetil is still debated, due to conflicting results from randomized clinical trials. This retrospective study aimed to compare 3‐year rejection‐free survival and adverse effects between adult kidney transplant recipients (KTRs) with or without mycophenolate mofetil model‐informed precision dosing (MIPD). MIPD is defined here as mycophenolic acid area under the curve (AUC0–12h) estimation using a limited sampling strategy, pharmacokinetic model… Show more
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