Betelkauen und Leukoplakie

Hp, Forlen; Hornstein, O. P.; Stuettgen, G

doi:10.1007/bf00515380

Cited by 10 publications

(4 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…All white lesions showing the characteristic Wickham's striae were clinically diagnosed as (10) 1965 New Guinea 753 ZACHARiAHcr ff/. White changes limited to the mucosa of the alveolar ridges in denture wearers were registered as examples of frictional lesions and were therefore not included in the leukoplakia group.…”

Section: Methodsmentioning

confidence: 99%

Prevalence study of oral leukoplakia in a selected population of 1000 patients from the Netherlands

Hogewind

Waal

1988

Comm Dent Oral Epid

View full text Add to dashboard Cite

A survey of a special population, the outpatients of a Department of Oral Surgery of a Teaching Hospital in Amsterdam, revealed a comparatively low prevalence rate for oral leukoplakia of 14/1000 patients (1.4%). No difference was found in the age distribution compared with similar investigations elsewhere in the world. However, in contrast with previous findings, which show a significant difference between prevalences of leukoplakia for men and women, leukoplakia was equally distributed between both sexes.

show abstract

Section: Methodsmentioning

confidence: 99%

Prevalence study of oral leukoplakia in a selected population of 1000 patients from the Netherlands

Hogewind

Waal

1988

Comm Dent Oral Epid

View full text Add to dashboard Cite

show abstract

“…They felt that the presence of white leukoplakic patches traced the pathway along which the lime must be continually deposited. Forlen et al (1965) have reported a correlation between the use of lime and a high incidence of leukoplakia in these same people. Leukoplakia in all these studies rightly denotes just the clinical presence of white patches.…”

mentioning

confidence: 83%

“…It has already been mentioned that lime has been correlated many years ago to the causation of leukoplakia (Fells, 1908;Orr, 1933;Bentall, 1908;Balendra, 1949). More recently, detailed surveys have been reported by Atkinson et al (1964) andForlen et al (1965). Atkinson et al studying the oral mucosa of islanders in New Guinea mention their custom of trailing the mucosal surface with a stick dipped in shell lime, subsequent to chewing the betel nut.…”

mentioning

confidence: 99%

Histological changes in the oral mucosa of the wistar rat treated with commercial lime (calcium hydroxide)--an optical and submicroscopic study

Sirsat¹,

Kandarkar²

1968

Br J Cancer

View full text Add to dashboard Cite

THE high incidence of oral cancer in different population groups in many south-east Asian nations has been stressed repeatedly in early and recent reports (Orr, 1933; Balendra, 1949; Cooray, 1944; Khanolkar, 1959; Muir, 1962; Pindborg, 1965). In India, and elsewhere, epidemiological and biological investigations have been done, or are in progress, on any possible correlation between the habitual use of the betel chew or " pan " and oral cancer. The involvement of the main constituents of " pan "-betel leaf (Piper betel), betel nut (Areca catechu), tobacco (Nicotiana tabacum), slaked shell or stone lime (slaked calcium hydroxide) and catechu (Acacia catechu) have also been considered individually or in combination (Mody and Ranadive, 1959;Muir and Kirk, 1960;Dunham, Muir and Hamner, 1966). The role of lime appears rather controversial, though some reports do suggest its correlation with the occurrence of oral cancer. It was therefore considered worthwhile to study the effects of slaked commercial lime on the oral mucosa of laboratory animals. The main aims of the study were to evaluate the part played by lime in the causation of oral malignancy or of oral conditions considered to be precancerous and the trauma it caused to epithelial and subepithelial tissue. This paper reports the histological changes produced on short term and prolonged application of lime to the oral mucosa of normal, diet conditioned and hormone treated Wistar rats. MATERIAL AND METHODSOne hundred and thirty-nine weanling Wistar rats (66 male and 73 female) were divided into four experimental groups as follows:Group I-36 animals on standard laboratory diet (wheat 66%; cracked lentils 15%; pea nut 5%; fish meal 7 %, shark liver oil 1%, sesame oil 1%).Group 11-35 animals on a protein deficient diet (milled rice 1000 g.; NaCl 10 g.; vegetable oil 50 ml.; cod liver oil 20 ml.; B-complex tablets (100 mg.) 3 tablets).Group llI-36 animals on a vitamin B deficient diet (Sucrose 34.5%; corn starch 34.0%; vegetable oil (vitamin A + D -700 Units) 6-7%; vitamin free casein 20%; NaCl 1.0%; CaCO3 0.5%).Group IV-32 animals on standard laboratory diet, pretreated locally with deoxycorticosterone acetate (DOCA). The hormone (Decortone-Cipla Ltd., Bombay) was injected on the palate biweekly in a dose of 1 mg. per injection.

show abstract

“…In Querschnittserhebungen lag die Streubreite der Prävalenz von Leukoplakien vor der WHO-Definition von 1978 zwischen 0,2% [15] und 17% [7], danach zwischen 1,4% [11] und 10,5% [3]. In Querschnittserhebungen lag die Streubreite der Prävalenz von Leukoplakien vor der WHO-Definition von 1978 zwischen 0,2% [15] und 17% [7], danach zwischen 1,4% [11] und 10,5% [3].…”

Section: Diskussionunclassified