Betamethasone Valerate in Foam Vehicle Is Effective with Both Daily and Twice a Day Dosing: A Single-Blind, Open-Label Study in the Treatment of Scalp Psoriasis

Abstract

BMV foam is effective for scalp psoriasis with both once-a-day and twice-a-day use. This feature of the BMV foam is encouraging for expected improvement in clinical use.

Topical corticosteroids in plaque psoriasis: a systematic review of efficacy and treatment modalities

“…Eighteen trials focused on the use of topical steroids for scalp psoriasis 53–56,58–71 . Sixteen were between‐patient 53–56,58–66,68–70 and two were within‐patient studies 67,71 .…”

“…Eighteen trials focused on the use of topical steroids for scalp psoriasis 53–56,58–71 . Sixteen were between‐patient 53–56,58–66,68–70 and two were within‐patient studies 67,71 . Treatment duration ranged from 2 to 8 weeks with the majority of durations being less than 6 weeks 27,53–56,59–63,66–69,71 The number of enrolled patients varied from 42 to 1417 patients according to the trial (mean 395 patients).…”

“…Sixteen were between‐patient 53–56,58–66,68–70 and two were within‐patient studies 67,71 . Treatment duration ranged from 2 to 8 weeks with the majority of durations being less than 6 weeks 27,53–56,59–63,66–69,71 The number of enrolled patients varied from 42 to 1417 patients according to the trial (mean 395 patients). Criteria for success was at least 75% improvement in initial psoriasis severity in seven trials 53,54,56,59,60,63,69 and at least 90% (clear or almost clear) in seven trials 55,58,61,64,66,70,71 .…”

“…Criteria for success was at least 75% improvement in initial psoriasis severity in seven trials 53,54,56,59,60,63,69 and at least 90% (clear or almost clear) in seven trials 55,58,61,64,66,70,71 . In four studies 27,62,67,68 , efficacy could not be assessed according to the definition of treatment success. A total of 40–75% patients across studies experienced more than 75% of initial scalp psoriasis improvement and from 43% to 90% experienced more than 90% initial psoriasis improvement as displayed in Fig.…”

Management of scalp psoriasis: current perspectives

“… 32 Another trial on 79 patients showed that once daily application of BMV 0.12% foam was as effective as twice daily application for 4 weeks. 33 This is important given that once daily efficacious treatment has a much higher adherence rate as compared to twice daily treatments. 34 …”