Betaine postpones hyperglycemia‐related senescence in ovarian and testicular cells: Involvement of RAGE and β‐galactosidase
Neda Mohammadi,
Mina Hemmati,
Behrouz Motlagh
et al.
Abstract:The structural and functional disorders of the testis and ovary are one of the main complications of hyperglycemia. Betaine is a trimethyl glycine with antioxidant, antidiabetic, and anti‐inflammatory potential. The aim of this study is to investigate the potential of betaine on the expression of aging and oxidative stress markers in ovarian and testicular cells under hyperglycemic conditions. Testicular and ovarian cells were subjected to four different conditions, including normal glucose and hyperglycemia, … Show more
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