Beta-Lactams and Tetracyclines

Buckler, Rebecca A.; Mitchell, Meghan T.; Peahota, Michelle M.; Gallagher, Jason C

doi:10.1016/bs.seda.2018.07.014

Cited by 5 publications

(1 citation statement)

References 36 publications

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“…Both have activity in the presence of beta-lactamases, both penicillin and cephalosporins, against Gram-negative and Gram-positive bacteria. (Sharon, 2007), (Rebecca, 2018) In several studies, it was stated that various guidelines do not recommend third-generation cephalosporin antibiotics such as ceftriaxone and ceftazidime for use as prophylactic antibiotics. This is because most of these drugs have a relatively higher price while their activity is lower than cefazolin in preventing bacterial growth of Staphylococcus sp.…”

Section: Postoperative Prophylactic Antibioticsmentioning

confidence: 99%

An Overview of Pre-Operative and Post-Operative Antibiotic Use in Inpatients in Orthopedic Surgery at Dr. H. Moch. Ansari Saleh Banjarmasin

Nizar,

Ariyanto

2024

jmhs

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Preoperative and postoperative antibiotics are included in prophylactic antibiotics, which aim to reduce the risk of surgical wound infection. Surgical Site Infection (SSI) is one of the problems of healthcare-associated infections (HAIs). Dr. Hospital H. Moch. Ansari Saleh Banjarmasin is a government hospital that provides many orthopedic surgical procedures and has data related to antibiotic use. This study aims to determine the description of the use of antibiotics as preoperative and postoperative prophylaxis. The research method included a descriptive observational study with a cross-sectional design on medical record data of surgical patients at Dr. RSUD. H. Moch. Ansari Saleh Banjarmasin in August–December 2023, which was taken using a purposive sampling technique with a retrospective approach. Results: 133 samples met the inclusion criteria. The majority of patients were aged 17–25 years (25.6%), the gender was predominantly male (62%), the length of stay was at most 2 days (40.6%), the type of surgery was clean (82%), and they did not have comorbidities (83%). Research shows that cefazolin is most widely used as preoperative prophylaxis by 123 people (92%) and postoperatively by 79 people (59.4%). The study concluded that the most widely used antibiotic for patients undergoing orthopedic surgery at RSUD, Dr. H. Moch. Ansari Saleh Banjarmasin, is cefazolin.

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Section: Postoperative Prophylactic Antibioticsmentioning

confidence: 99%