Beta-glucan enhanced immune response to Newcastle disease vaccine and changed mRNA expression of spleen in chickens

Cao, Liru; Li, Jun; Zhang, Jianrong; Huang, Huan; Gui, Fuxing; Xu, Wei; Zhang, Li; Bi, Shicheng

doi:10.1016/j.psj.2022.102414

Cited by 4 publications

(5 citation statements)

References 47 publications

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“…The initial drop can be attributed to 2 possibilities: the suboptimal analyzed protein-to-energy ratio for the HY group (a 12% difference between the 2 diets) ( Gous et al, 2018 ; Aftab, 2019 ) and the fact that the birds were already challenged due to feed restriction for both treatment groups and the incorporation of HY, which is a rich source of β-glucans and mannans ( Maina et al, 2022 ; Thomas et al, 2022 ), may potentially have affected the immune system ( Volman et al, 2008 ). Arguably, a fraction of nutrients that would ordinarily be channeled to growth and maintenance was transferred to immune protein production, as possibly indicated by the high splenic mass in pullets fed HY ( Bi et al, 2022 ; Cao et al, 2023 ).…”

Section: Discussionmentioning

confidence: 99%

“…In chickens, the spleen is a storage site for white blood cells and an essential organ where immune cells are activated. Yeast β-glucans and oligo-mannans have been demonstrated to boost the circulation of new immune cells, improve macrophage activity, promote phagocytosis, increase the number of goblet cells and production of mucin-2, trigger heightened expression of intestinal tight-junctions, and act as potent anti-inflammatory immunomodulators in poultry ( Schwartz and Vetvicka, 2021 ; Bi et al, 2022 ; Cao et al, 2023 ). Antibody titers have been used to measure the effectiveness of vaccination or the level of infection in a flock, more so for infections of commercial interest, such as infectious bronchitis ( Gu et al, 2022 ) and Newcastle diseases ( Mao et al, 2022 ).…”

Section: Discussionmentioning

confidence: 99%

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Response of broiler breeder pullets when fed hydrolyzed whole yeast from placement to 22 wk of age

Maina,

Schulze,

Kiarie

2024

Poultry Science

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Response of broiler breeder pullets when fed hydrolyzed whole yeast from placement to 22 wk of age

Maina,

Schulze,

Kiarie

2024

Poultry Science

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“…In association with the differential regulation of the cytokine expression pattern, B. cereus was suggested to be involved in the activation and migration of B cells as well as vaccine antigen presentation (129). This holds true also for β-glucan, which is derived from yeast, and was shown to enhance hemagglutinating antibody levels after NDV vaccination (130). Molecular adjuvants may enhance the humoral immune response, especially in the context of poorly immunogenic peptide vaccines.…”

Section: Acquired Immune Responsesmentioning

confidence: 91%

The Immunological Basis for Vaccination

Rautenschlein,

Schat

2023

Avian Diseases

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Vaccination is crucial for health protection of poultry and therefore important to maintaining high production standards. Proper vaccination requires knowledge of the key players of the well-orchestrated immune system of birds, their interdependence and delicate regulation, and, subsequently, possible modes of stimulation through vaccine antigens and adjuvants. The knowledge about the innate and acquired immune systems of birds has increased significantly during the recent years but open questions remain and have to be elucidated further. Despite similarities between avian and mammalian species in their composition of immune cells and modes of activation, important differences exist, including differences in the innate, but also humoral and cell-mediated immunity with respect to, for example, signaling transduction pathways, antigen presentation, and cell repertoires. For a successful vaccination strategy in birds it always has to be considered that genotype and age of the birds at the time point of immunization as well as their microbiota composition may have an impact and may drive the immune reactions into different directions. Recent achievements in the understanding of the concept of trained immunity will contribute to the advancement of current vaccine types helping to improve protection beyond the specificity of an antigen-driven immune response. The fast developments in new omics technologies will provide insights into protective B-and T-cell epitopes involved in cross-protection, which subsequently will lead to the improvement of vaccine efficacy in poultry.RESUMEN. Estudio recapitulativo-Bases inmunológicas de la vacunación. La vacunación es crucial para la protección de la salud de las aves comerciales y por lo tanto, importante para mantener altos estándares de producción. Una vacunación adecuada requiere el conocimiento de los factores clave del sistema inmunológico bien orquestado de las aves, su interdependencia y su delicada regulación y posteriormente, los posibles modos de estimulación a través de antı genos y adyuvantes de las vacunas. El conocimiento sobre los sistemas inmunológicos innato y adquirido de las aves ha aumentado significativamente durante los últimos años, pero quedan preguntas abiertas que deben dilucidarse con profundidad. A pesar de las similitudes entre las especies de aves y mamı feros en la composición de células inmunes y modos de activación, existen diferencias importantes, incluidas las diferencias en la inmunidad innata, pero también en la inmunidad humoral y en la mediada por células, con respecto a las vı as de transducción de señales, la presentación de antı genos. y repertorios celulares. Para una estrategia de vacunación exitosa en las aves, siempre se debe considerar que el genotipo y la edad de las aves en el momento de la inmunización, ası como la composición de su microbiota pueden tener un impacto y pueden impulsar las reacciones inmunes en diferentes direcciones. Los logros recientes en la comprensión del concepto de inmunidad entrenada contribuirán al avance...

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“…P. sajor-caju SMS has slightly higher carbohydrate and fat levels. However, in fruiting bodies, P. ostreatus surpasses P. sajor-caju in protein content (30.40 g kg −1 vs. 19.23 g kg −1 ) and ash content (9.80% vs. 6.32%), while P. sajor-caju fruiting bodies show higher carbohydrate and fat levels [53,54]. In summary, the valorization of waste mushroom substrate for agro-applications (e.g., compost, plant growing media and biofertilizer) as alternative energy sources deserves consideration in the future.…”

Section: Valorization Of Oyster By-productsmentioning

confidence: 92%

“…They encompass β-glucans, shown to promote intestinal health, thereby strengthening the immune system and potentially enhancing poultry meat quality. Introducing mushroom derivatives into poultry diets has the potential to enhance overall health and productivity, offering a natural and sustainable alternative to frequently employed antimicrobial medications [53]. The utilization of by-products from food industries and agronomy is crucial for the implementation of sustainable farming practices.…”

Section: A Comprehensive Overviewmentioning

confidence: 99%

Pleurotus ostreatus Mushroom: A Promising Feed Supplement in Poultry Farming

Törős,

El-Ramady,

Béni

et al. 2024

Agriculture

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Pleurotus ostreatus (Jacq. ex Fr.) P. Kumm mushrooms are cultivated on diverse by-products based on substrates that hold promise for mitigating antibiotic usage in the poultry industry and reducing environmental pollution. By incorporating agricultural by-products into mushroom cultivation, the functionality of the mushroom products can be increased, then the final product can be a more effective feed supplement. After mushroom cultivation, spent mushroom substrate (SMS) can be valorized, due to the presence of huge amounts of bioactive compounds like β-glucan, chitin, polyphenols, and flavonoids related to mycelia. As a prebiotic and antimicrobial feed supplement, these mushrooms positively influence gut microbiota, intestinal morphology, and thus overall poultry well-being. This article underscores the potential of solid-state fermentation (SSF) to enhance the bioactivity of oyster mushrooms and their derivatives, offering a cost-effective and efficient strategy for transforming unconventional feeding materials. Moreover, it emphasizes broader implications, including the reduction of antibiotic dependence in poultry farming, highlighting the promising integration of oyster mushrooms and their derivatives for sustainable and environmentally conscious poultry production.

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Beta-glucan enhanced immune response to Newcastle disease vaccine and changed mRNA expression of spleen in chickens

Cited by 4 publications

References 47 publications

Response of broiler breeder pullets when fed hydrolyzed whole yeast from placement to 22 wk of age

Response of broiler breeder pullets when fed hydrolyzed whole yeast from placement to 22 wk of age

The Immunological Basis for Vaccination

Pleurotus ostreatus Mushroom: A Promising Feed Supplement in Poultry Farming

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