Beta-2-Microglobulin (B2m) Adsorption on Activated Charcoal (AC)

Anelli, Adriana; Gallieni, Maurizio; Padovese, P.; Colantonio, G.; Barbesti, S.; Brancaccio, Diego

doi:10.1007/978-1-4613-0865-2_65

Cited by 2 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Combined use of the day-and nighttime system may further enhance plasma clearance, especially for creatinine and phosphate (3.0-fold and 2.7-fold, respectively, vs APD/CAPD [6]), which may allow for a more liberal diet and reduction of phosphate binders. Since most organic waste solutes bind efficiently to activated carbon similar to creatinine [4,48], we expect that clearance of these solutes may also increase.…”

Section: Discussionmentioning

confidence: 99%

In vitro efficacy and safety of a system for sorbent-assisted peritoneal dialysis

Gelder

Ligabue

Giovanella

et al. 2020

American Journal of Physiology-Renal Physiology

View full text Add to dashboard Cite

A system for sorbent-assisted peritoneal dialysis (SAPD) was designed to continuously recirculate dialysate via a tidal mode using a single lumen peritoneal catheter with regeneration of spent dialysate by means of sorbent technology. We hypothesize that SAPD treatment will maintain a high plasma-to-dialysate concentration gradient and increase the mass transfer area coefficient of solutes. Thereby, the SAPD system may enhance clearance while reducing the number of exchanges. Application is envisaged at night as a bedside device (12 kg, nighttime system). A wearable system (2.0 kg, daytime system) may further enhance clearance during the day. Urea, creatinine, and phosphate removal were studied with the daytime and nighttime system ( n = 3 per system) by recirculating 2 liters of spent peritoneal dialysate via a tidal mode (mean flow rate: 50 and 100 mL/min, respectively) for 8 h in vitro. Time-averaged plasma clearance over 24 h was modeled assuming one 2 liter exchange/day, an increase in mass transfer area coefficient, and 0.9 liters ultrafiltration/day. Urea, creatinine, and phosphate removal was 33.2 ± 4.1, 5.3 ± 0.5, and 6.2 ± 1.8 mmol, respectively, with the daytime system and 204 ± 28, 10.3 ± 2.4, and 11.4 ± 2.1 mmol, respectively, with the nighttime system. Time-averaged plasma clearances of urea, creatinine and phosphate were 9.6 ± 1.1, 9.6 ± 1.7, and 7.0 ± 0.9 mL/min, respectively, with the nighttime system and 10.8 ± 1.1, 13.4 ± 1.8, and 9.7 ± 1.6 mL/min, respectively, with the daytime and nighttime system. SAPD treatment may improve removal of uremic toxins compared with conventional peritoneal dialysis, provided that peritoneal mass transport will increase.

show abstract

Section: Discussionmentioning

confidence: 99%

In vitro efficacy and safety of a system for sorbent-assisted peritoneal dialysis

Gelder

Ligabue

Giovanella

et al. 2020

American Journal of Physiology-Renal Physiology

View full text Add to dashboard Cite

show abstract

La Sindrome Del Tunnel Carpale Del Paziente Uremico

Bandini

Ceruso²,

Lauri³

et al. 1991

Giornale di Tecniche Nefrologiche e Dialitiche

View full text Add to dashboard Cite

L a Sindrome del Tunnel Carpale (ST.C.) euna patologia determinata dalla compressione del nervo mediano a livello del canale del carpo, cioe in quello spazio cilindrico costituito dalla concavita delle ossa del carpo e chiuso, palmarmente, dal legamento trasverso del carpo. Nell'etiopatogenesi della S.T.c. si distingue una forma primitiva, idiopatica, che colpisce donne in eta postmenopausale ed una forma secondaria.

show abstract

Beta-2-Microglobulin (B2m) Adsorption on Activated Charcoal (AC)

Cited by 2 publications

References 4 publications

In vitro efficacy and safety of a system for sorbent-assisted peritoneal dialysis

In vitro efficacy and safety of a system for sorbent-assisted peritoneal dialysis

La Sindrome Del Tunnel Carpale Del Paziente Uremico

Contact Info

Product

Resources

About