Bestrahlungsplanung rückenmarksnaher Tumoren unter Zuhilfenahme der CT-Myelographie

Plathow, Christian; Thilmann, Christoph; Delorme, Stefan; Stippich, Christoph; Wannenmacher, M; Debus, Jürgen

doi:10.1007/pl00002413

Cited by 8 publications

(1 citation statement)

References 22 publications

(31 reference statements)

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“…Spinal chordomas are even more challenging to treat with RT, because the immobilization for extracranial targets is less reliable, the tolerance dose of the spinal cord is low and stabilization with metal implants often produces artefacts on post surgical MRI and CT scans that complicate precise target volume definition and reduces accuracy of dose calculation (Plathow et al 2001). Furthermore, the vicinity to the spinal cord limits the achievable dose to the target volume.…”

Section: Rt Of Chordomasmentioning

confidence: 99%

Treatment planning intercomparison for spinal chordomas using intensity-modulated photon radiation therapy (IMRT) and carbon ions

et al. 2003

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Spinal chordomas cannot be treated with an effective dose using conventional radiation therapy (RT) without exceeding the tolerance dose of the spinal cord while ensuring sufficient target coverage at the same time. In this study we investigate the potential physical advantages of combined photon intensity-modulated radiation therapy (IMRT) and raster-scanned carbon ion RT over photon IMRT alone. For a representative patient we generated a carbon ion RT plan and a photon IMRT plan. Additionally, combined plans consisting of both carbon ions and photon IMRT were calculated using ratios of 20:40 GyE, 30:30 GyE and 40:20 GyE. The best target coverage was obtained using carbon ions alone. Using a combination of photon IMRT and carbon ions, the target coverage was better than with photon IMRT alone. Due to the applied dose constraints, the sparing of the spinal cord was comparable for all plans. Using carbon ions alone, the non-target tissue volume irradiated to at least 30 GyE/50.4 GyE was reduced by 72%/84% compared to photon IMRT alone. These advantages were evident even with combined techniques. The actually delivered dose distribution is expected to be more dependent on patient misalignment with carbon ions compared with photon IMRT. A combination of carbon ions and photon IMRT might be preferable in order to profit by the physical advantages of carbon ions while ensuring a safe treatment.

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Section: Rt Of Chordomasmentioning

confidence: 99%

Treatment planning intercomparison for spinal chordomas using intensity-modulated photon radiation therapy (IMRT) and carbon ions

et al. 2003

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Spinal Radiosurgery

Gibbs¹,

Atalar²,

Wang³

2014

Stereotactic Body Radiotherapy

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The Electronic Portal Imaging System Siemens Beamview Plus ® Versus the Conventional Verification Films CEA-TVS ® and DuPont CQL-7 ®

Gagel

Schramm

Harms

et al. 2002

Strahlentherapie und Onkologie

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As data of EPIDS are digital, images can be postprocessed and enhanced in a wide variety of ways. Using this tool the electronic portal imaging device provides images that, in terms of visual image quality, are at least comparable to the two evaluated types of radiographic films and also have the added advantage that such images are stored and can be transferred electronically being presupposition for digital patient documentation.

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Bestrahlungsplanung rückenmarksnaher Tumoren unter Zuhilfenahme der CT-Myelographie

Cited by 8 publications

References 22 publications

Treatment planning intercomparison for spinal chordomas using intensity-modulated photon radiation therapy (IMRT) and carbon ions

Treatment planning intercomparison for spinal chordomas using intensity-modulated photon radiation therapy (IMRT) and carbon ions

Spinal Radiosurgery

The Electronic Portal Imaging System Siemens Beamview Plus ® Versus the Conventional Verification Films CEA-TVS ® and DuPont CQL-7 ®

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