Berry anthocyanin-based films in smart food packaging: A mini-review

Neves, Dina; Andrade, Paula B.; Videira, Romeu A.; Freitas, Victor de; Cruz, Luís

doi:10.1016/j.foodhyd.2022.107885

Cited by 57 publications

(17 citation statements)

References 82 publications

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“…4 B C 0 and C 1 ). As the concentration of OH − increases with pH, anthocyanins mainly exist in quinonoid bases ( Neves et al, 2022 ). Meanwhile, the color of the solution became darker and changed from purple to blue-violet (pH 8.0–9.0), concurrent with an increase in absorbance ( Cheng et al, 2022 ).…”

Section: Resultsmentioning

confidence: 99%

“…Anthocyanins (ACNs) widely distributed in fruits and vegetables such as sweet potatoes, red cabbage, cranberry, and raspberry ( Cai et al, 2020 ; Neves et al, 2022 ). A large number of studies demonstrated that ACNs from natural sources possess a wide spectrum of potential functional properties, including anti-oxidant, anti-inflammation, anti-aging, anti-cancer, and neuro-protection ( Sreerekha et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

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Enzymatic acylation of cyanidin-3-O-glucoside in raspberry anthocyanins for intelligent packaging: Improvement of stability, lipophilicity and functional properties

Yang

Liu

Shao

et al. 2022

Current Research in Food Science

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Enzymatic acylation of cyanidin-3-O-glucoside in raspberry anthocyanins for intelligent packaging: Improvement of stability, lipophilicity and functional properties

Yang

Liu

Shao

et al. 2022

Current Research in Food Science

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“…Additionally, film sizing was performed to a corresponding area density between 7.82 and 12.19 mg × cm −2 . The plasticizer (glycerin) with the best compatibility related to β-glucan and most popular for anthocyanin-based films [ 19 , 20 ] was added to the all polymer samples, while the soybean oil was included in three different samples as 2% ( w / w ) of the total solids (β-glucan, sodium alginate, and bilberry juice).…”

Section: Resultsmentioning

confidence: 99%

Formulation of Fast Dissolving β-Glucan/Bilberry Juice Films for Packaging Dry Powdered Pharmaceuticals for Diabetes

Avramia

Amariei

2022

Plants

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The aim of this study was to develop fast dissolving films based on β-glucan and bilberry juice due to the bioactive potential of β-glucan and antidiabetic effect of bilberry juice. The benefit of incorporation of bioactive compounds into the films is due to the removal of unnecessary excipients and to confer protection as well as increase stability and shelf life to the packaged product. Due to the fast dissolving requirements of the European Pharmacopeia, which reduced the dissolution time from 180 to 60 s, indicating less than a minute, hygroscopic materials, such as sodium alginate and a suitable plasticizer, such as glycerin were incorporated. Moreover, the influence of ingredients and surfactants, such as soybean oil was studied in the design of fast dissolving films. Additionally, the steady state rate water vapor transmission rate (WVTR), water vapor permeability (WVP), and FT-IR spectroscopy tests were performed at high resolution to ensure the reliability of the films and composition as well as to validate the results. Our data suggest that the addition of surfactants contributed to the development of fast dissolving films without influencing the diffusion of water vapor. Low levels of WVTR and short dissolution time made from β-glucan and bilberry juice are a convenient candidate for packaging dry powdered pharmaceuticals for diabetes.

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“…SC -Nanophytosomes, prepared with a concentration of 600 µM of algae membrane polar lipids and 0.5 mg/mL of EAE-extract, exhibit the typical absorption bands of elderberry phenolics with a maximum at 280 (as the shoulder), 350, and 520 nm that are preserved during the successive dialysis against buffers with pH of 6.4, 2.0 and 7.4 ( Figure 1 B). The absorption band with a maximum at 520 nm is typical of the anthocyanins in flavylium cation form (acidic form) since its blue quinoidal bases, the dominant form in aqueous solution with pH > 3, exhibited a maximum at 430 nm [ 23 ]. Therefore, the pH changes in the external environment do not affect anthocyanins in the SC -Nanophytosomes, suggesting that they form a stable complex with algae membrane polar lipids.…”

Section: Resultsmentioning

confidence: 99%

Brain Effects of SC-Nanophytosomes on a Rotenone-Induced Rat Model of Parkinson’s Disease—A Proof of Concept for a Mitochondria-Targeted Therapy

Mendes

Peixoto

Oliveira

et al. 2022

IJMS

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Mitochondria are an attractive target to fight neurodegenerative diseases due to their important functions for cells and the particularly close relationship between the functional connectivity among brain regions and mitochondrial performance. This work presents a mitochondria-targeted therapy designed to modulate the functionality of the mitochondrial respiratory chain and lipidome, parameters that are affected in neurodegeneration, including in Parkinson’s disease (PD). This therapy is supported by SC-Nanophytosomes constructed with membrane polar lipids, from Codium tomentosum, and elderberry anthocyanin-enriched extract, from Sambucus nigra L. SC-Nanophytosomes are nanosized vesicles with a high negative surface charge that preserve their properties, including anthocyanins in the flavylium cation form, under conditions that mimic the gastrointestinal tract pH changes. SC-Nanophytosomes, 3 µM in phospholipid, and 2.5 mg/L of EAE-extract, delivered by drinking water to a rotenone-induced PD rat model, showed significant positive outcomes on disabling motor symptoms associated with the disease. Ex vivo assays were performed with two brain portions, one comprising the basal ganglia and cerebellum (BG-Cereb) and the other with the cerebral cortex (C-Cortex) regions. Results showed that rotenone-induced neurodegeneration increases the α-synuclein levels in the BG-Cereb portion and compromises mitochondrial respiratory chain functionality in both brain portions, well-evidenced by a 50% decrease in the respiratory control rate and up to 40% in complex I activity. Rotenone-induced PD phenotype is also associated with changes in superoxide dismutase and catalase activities that are dependent on the brain portion. Treatment with SC-Nanophytosomes reverted the α-synuclein levels and antioxidant enzymes activity to the values detected in control animals. Moreover, it mitigated mitochondrial dysfunction, with positive outcomes on the respiratory control rate, the activity of individual respiratory complexes, and the fatty acid profile of the membrane phospholipids. Therefore, SC-Nanophytosomes are a promising tool to support mitochondria-targeted therapy for neurodegenerative diseases.

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Berry anthocyanin-based films in smart food packaging: A mini-review

Cited by 57 publications

References 82 publications

Enzymatic acylation of cyanidin-3-O-glucoside in raspberry anthocyanins for intelligent packaging: Improvement of stability, lipophilicity and functional properties

Enzymatic acylation of cyanidin-3-O-glucoside in raspberry anthocyanins for intelligent packaging: Improvement of stability, lipophilicity and functional properties

Formulation of Fast Dissolving β-Glucan/Bilberry Juice Films for Packaging Dry Powdered Pharmaceuticals for Diabetes

Brain Effects of SC-Nanophytosomes on a Rotenone-Induced Rat Model of Parkinson’s Disease—A Proof of Concept for a Mitochondria-Targeted Therapy

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