Benzoylene Urea

Abstract

Benzoylene urea product: benzoylene urea

Design and Synthesis of New Tetrazolyl- and Carboxy-biphenylylmethyl-quinazolin-4-one Derivatives as Angiotensin II AT1 Receptor Antagonists

“…Mass spectra were carried out at the EPSRC National Mass Spectrometry Service Centre, Chemistry Department, University of Wales, Swansea, UK or The Microanalytical Centre, Cairo University, Egypt. Preparation of 2-bromobenzoic acid tert -butyl ester ( I ), 4‘-methylbiphenyl-2-carboxylic acid tert -butyl ester ( II ), ,− 4‘-bromomethyl-biphenyl-2-carboxylic acid tert -butyl ester ( VI ), ,− 4‘-bromomethyl-biphenyl-2-carbonitrile ( VII ), , 5-(4‘-methylbiphenyl-2-yl)-2-trityl-2 H -tetrazole ( VIII ), ,− 5-(4‘-bromomethyl-biphenyl-2-yl)-2-trityl-2 H -tetrazole ( IX ), , 1 H -quinazoline-2,4-dione ( X ), − and 2-methylsulfanyl-3 H -quinazolin-4-one ( XVI ) 35 were performed according to reported procedures. Compound XV was purchased from Aldrich.…”

The Detection of Glycine from the Treatment of Glyoxylic Acid with iron(II) Sulfate and Ammonia in Water

“…2-Amino-4-nitrobenzoic acid was converted to 7-nitroquinazoline-2,4-dione by condensation with KOCN following a preparation for making quinazoline-2,4-dione (Scheme 3). 19 6-Nitroquinazoline-2,4-dione has been used in nucleotide studies and the 7-nitro isomer was previously unknown. 20 In summary a potential prebiotic synthesis of the amino acid glycine is proposed via the reductive amination of glyoxylic acid with soluble Fe(II)SO 4 and ammonia.…”

Recent advances in synthesis of quinazoline‐2,4(1H,3H)‐diones: Versatile building blocks in N‐heterocyclic compounds

“…In addition, the synthesizing of quinazoline‐2,4( 1H,3H )‐dione 15 by Lange et al has been described. [ 43 ] As shown in Scheme 5, the nitration was carried out using the procedure described by Mendenhall, [ 44 ] because it uses low temperatures and the most favorable conditions for this type of reaction.…”